- Transcript 'KH2012:KH.C4.91.v1.A...'
Transcript Model
Transcript Id
KH2012:KH.C4.91.v1.A.SL1-1
Possible name(s)
KMT2A; SETD1A; SETD1B
Gene model
Location
KhC4 [440,457 / 457,120]
Amino acid sequence
Length: 1,848
>KH.C4.91.v1.A.SL1-1
TMKKQQPAAAFRGNFKVIVDPQLKKGQEKLVRFNGTEYSCENHGQAPVAVRDPRARVSRL
WSRKERIDLPVPRYKVDENYTGDVPPREVTFSKLNDNITKQFMEQMCSKYGKLERVRVYH
HPKTNKHMGLAKVVFASIKSASMCISNLHQTSIMGNIINAEIDSKGELLKHLFNKIIRGE
ILAETMPDVIRHTQEKPITRPVPVKDRRKSSQEDPRRRSSSDRKSSMEQTTSSHGPKTPP
STLIDGKPNDNKQDLLNMEGARVPMHSNTKSSDNESGVSDEATRQHQNPRVNKRKVKKKK
KSRKYSRNSDSDTEMEKGKKGLPMWSTELEQRIENLLSEQNRKYNLDSTSRSSSHEFKST
SSTKSSDRKYSEQSGTDNDHSETAEESDVFDQASMSNHNHVETAELIDLEDGECSGDAEE
VHNGRSRKQSPVIQVMERAQHETSPDTKSERVSYSPSVVNSVNENSYHDNSPNQFPPSQS
PHRIVGRSIPTDSINYERRHEDRRRPPSPIELRSRSPFPQERYRHGGRSPEYIDRHHFDR
YPPRHRSPSFEHRHRRSPPPFELHRPRGRSPNFDHRGFHHGGYRGRMGSPGYMRPSDFPP
GHPEFNRRRSPSPGFSRRRRSISPVHPRYGIRREFEMSPRRDRYRRTPPDIGRHRREPSP
RFAEYDRHRRRSPGFHRDHHYHPPSSPDSRRQRDKRELPPEFQERWSRNRSQSPHHSHFR
RDTSPRHDSHMRRSRSNSRNCSRPRSRSPKLTDDRPYSPGDFAVEDNIESDVAIHTSVST
DAVESYSDSANHKKGRRKNNDSSDVGELQQISLDERLREMTGEAPDDGTPPHSPLLTEAE
VPVSDNHEDIPDGSDDMEISSGGSTHSPHLQEKQNFHPNQQSWQYNQQEMWNGFDPRFHL
PNQQPMWCPPAQRFPHNVPNGFIRPFMPDCPIDMKILPPPPPVIESMAFKVYEAWWDEQY
ALKNPKPAALKKTTVHQNQASLKTESNINTEQPVVDKVKAESKPAGKLPALLNTFDPLNW
AKGSMEMDGFRIGLGLRSAISKMPSFRVKKPTPSFDEKSKLIGDKSKAETKSEQEVQRRK
RIRQTLDSEGEEDDESDYSDVDDKKTKIIGRLDVDEVFSTSSSSQSSEDEDDDQESSEEE
SDEGSDEDVEPLIGVKRTIHDDVRSEPPKKKKKDNIDEVKIEAEVSKPTNRSDDVIKAAS
MLSELQSGKSLLPPSAPANIVTSQTLKHVHPKKRFRLISTDASGHEISERLRSDDELSAM
SDKEKAALEVLTDMKSTPERRMSTVNRLSSSDSSDQPILPTTPGRQHSEVTSVFSPPLTP
APSSRSIFSHDTHPSSDMRIPITPGSDTNLSDRKKSDSKELEAVQALLSIKESQPPIPPL
SPPTPVSTKHQPLKKRADLRLTIPPKRSTSVLTQEDKDRMTALAEEHNYFATSPRVKPTS
SHIHPSLLQILEEHNYSCPPSQAPKTPLKKSQDEAPFLHNDVISTSESPASAAELVKLRH
GDSKMYKKIKQRTDQLYYEEKIKRSLVGRFRERTHMDDMRMMYNIWDRGLDVEDMKYLRQ
EYEDMLANPGTGGWVNDTHWVPHPATYFPDENDALTTSPDKRNKRKRRQARKDDISDIKP
HKTGCARSEGFYKVNDNTKLIQRKLMYRQADNTPQPKGRSKYANESASTSGVATEKSRET
RHMMRRIASEFGSDASDLLKYNQLMYRKKSVKFKRSHIHGWGLFAEETIGADEMVIEYVG
QLVRSLIADRREVDYTRRGIGSSYLFRIDSDHIIDATKCGNFARFMNHSCNPSCYAKVIA
VDGAKKIVIYSKDTIKPTDEITYDYKFPIEDVKIPCFCGAPNCRGTLN
Nucleotide sequence
Length: 5,988
>KH2012:KH.C4.91.v1.A.SL1-1
ATTCAAAAGTTGTGAGCAAAATGTGCTGCTTTGCAGCCAGAATGCTTCAAAATATATTTG
CTGTATATTACAAATGAACAATGAAGAAGCAACAACCTGCAGCCGCATTTCGTGGTAATT
TCAAAGTAATAGTTGATCCCCAACTAAAAAAAGGACAGGAAAAGTTGGTTCGGTTTAATG
GAACAGAATACAGCTGTGAGAACCATGGACAAGCACCTGTTGCTGTTCGTGATCCACGTG
CAAGAGTATCAAGATTATGGAGTCGAAAAGAAAGAATTGATCTTCCTGTACCAAGATATA
AGGTGGATGAGAACTACACTGGTGATGTACCACCAAGAGAAGTAACCTTTTCAAAATTAA
ACGATAATATCACCAAACAGTTCATGGAACAAATGTGTTCTAAGTATGGAAAACTTGAAA
GAGTACGTGTATACCATCATCCCAAAACGAACAAGCACATGGGACTTGCAAAGGTTGTTT
TTGCTTCCATCAAGTCTGCATCCATGTGTATATCTAATCTGCACCAAACTTCAATAATGG
GAAATATTATTAATGCCGAAATTGACAGTAAAGGTGAACTGTTAAAACATCTTTTCAATA
AAATAATTCGTGGAGAAATATTGGCTGAGACGATGCCAGATGTAATTCGACACACACAAG
AAAAACCAATCACTCGGCCAGTACCTGTTAAAGACAGAAGGAAATCATCTCAAGAAGATC
CAAGACGAAGGTCATCAAGTGATAGGAAGTCCTCCATGGAGCAAACAACATCCAGTCACG
GTCCAAAGACTCCTCCATCTACTCTTATTGATGGAAAGCCCAATGATAACAAACAAGACT
TGCTAAACATGGAGGGTGCAAGAGTTCCAATGCATTCAAATACCAAATCATCGGATAATG
AAAGTGGGGTTTCTGATGAAGCTACCAGACAGCACCAAAATCCCCGGGTAAACAAACGTA
AAGTTAAGAAAAAGAAAAAGTCTAGGAAATATAGCAGGAACTCTGATAGTGATACTGAAA
TGGAAAAAGGTAAAAAAGGATTACCCATGTGGTCCACTGAATTGGAACAACGTATTGAAA
ATTTATTATCCGAACAAAATCGTAAGTACAACCTTGATAGTACAAGTCGGTCGTCGAGCC
ATGAATTTAAAAGTACAAGCAGCACAAAATCTAGTGATCGGAAGTACAGTGAACAATCAG
GGACTGATAATGATCATTCAGAAACAGCTGAGGAAAGTGATGTTTTCGATCAAGCTTCCA
TGTCAAACCACAACCATGTAGAAACAGCTGAACTTATTGATTTGGAGGATGGTGAGTGCT
CCGGTGATGCAGAAGAAGTCCACAATGGAAGATCAAGGAAACAATCTCCAGTCATACAAG
TGATGGAAAGAGCGCAACATGAAACTTCTCCTGATACGAAATCTGAACGCGTTTCTTATT
CCCCTTCTGTGGTTAACTCTGTAAATGAAAATTCATACCACGATAACTCCCCCAATCAAT
TTCCTCCAAGTCAGTCACCCCACAGAATAGTAGGTAGAAGTATACCAACAGACTCAATAA
ACTATGAAAGACGACATGAAGATCGTCGGAGACCGCCCAGTCCAATTGAGTTAAGATCAC
GCAGTCCTTTCCCCCAAGAAAGGTATCGGCACGGTGGTCGAAGTCCAGAATACATTGATA
GACACCACTTTGACCGTTATCCACCAAGACACCGAAGCCCATCCTTTGAACATCGACACC
GGAGAAGTCCGCCACCTTTTGAACTTCATCGACCAAGGGGTCGTAGTCCAAACTTTGATC
ACCGCGGTTTCCACCACGGGGGTTATAGAGGAAGAATGGGAAGTCCTGGTTATATGCGAC
CATCAGATTTTCCACCTGGGCATCCTGAGTTCAACAGAAGAAGGAGTCCAAGTCCAGGGT
TTAGTCGTAGAAGAAGAAGTATCTCCCCCGTCCATCCAAGGTATGGGATTCGTAGGGAGT
TTGAAATGAGTCCCCGTCGAGATAGGTACCGACGAACACCACCAGATATCGGTCGCCATC
GTCGCGAACCTAGTCCTCGTTTTGCTGAGTATGATCGTCATAGAAGAAGAAGTCCTGGCT
TCCATAGAGATCATCATTACCATCCTCCCTCGAGCCCGGACTCTCGAAGGCAACGAGATA
AACGGGAACTTCCGCCAGAATTTCAGGAAAGATGGTCAAGAAACCGTTCCCAAAGTCCTC
ACCATTCACACTTCAGACGAGACACTTCACCCAGGCACGATAGTCACATGAGAAGATCGA
GATCCAATTCTAGAAATTGCTCAAGACCCCGATCTCGTTCCCCAAAACTCACAGATGATC
GACCTTACTCACCTGGTGACTTTGCTGTTGAAGATAATATTGAATCTGATGTTGCTATTC
ATACTTCTGTATCTACTGATGCAGTTGAATCTTATAGTGATTCTGCAAATCATAAGAAAG
GACGACGCAAAAACAATGATTCATCTGATGTTGGTGAACTACAGCAAATATCACTGGATG
AAAGGTTAAGAGAGATGACCGGGGAAGCCCCTGATGATGGGACACCTCCACACTCCCCAT
TATTAACTGAAGCAGAGGTTCCAGTGTCTGATAATCATGAAGACATACCGGATGGTTCGG
ACGATATGGAAATATCTTCAGGTGGTAGCACACACTCACCTCACTTACAGGAGAAACAAA
ACTTTCATCCAAACCAGCAATCATGGCAGTATAATCAACAAGAAATGTGGAATGGTTTTG
ATCCTAGATTTCATCTTCCCAACCAACAACCAATGTGGTGTCCTCCAGCACAAAGGTTTC
CACATAATGTTCCAAATGGTTTTATTCGACCTTTCATGCCAGATTGTCCGATTGACATGA
AAATATTACCACCCCCACCCCCTGTTATTGAATCAATGGCATTCAAAGTGTATGAAGCAT
GGTGGGACGAACAGTATGCACTCAAAAACCCAAAACCGGCGGCTCTAAAAAAGACAACTG
TCCATCAAAACCAAGCAAGTTTAAAAACTGAATCAAATATCAACACAGAACAACCAGTAG
TTGATAAAGTTAAAGCTGAAAGCAAACCTGCTGGTAAATTGCCAGCTTTGCTTAACACAT
TTGATCCACTTAATTGGGCTAAAGGTTCAATGGAAATGGATGGATTTCGAATTGGTCTTG
GACTTCGATCTGCCATCTCTAAGATGCCTTCATTTCGTGTCAAGAAACCAACTCCAAGCT
TTGATGAGAAATCAAAACTAATTGGTGACAAATCTAAAGCTGAAACGAAATCCGAACAAG
AGGTTCAACGAAGAAAGAGGATCCGACAAACACTTGATAGTGAGGGAGAGGAAGATGATG
AAAGTGATTATTCAGATGTGGACGACAAGAAAACAAAAATAATTGGTCGGCTTGATGTTG
ATGAAGTCTTCAGCACATCTTCATCATCTCAGAGCTCGGAAGATGAAGATGATGATCAGG
AGTCCAGTGAAGAGGAGAGTGATGAAGGATCGGATGAGGATGTTGAACCATTAATTGGAG
TGAAGAGGACAATACATGATGATGTGAGGAGTGAACCTCCGAAAAAGAAGAAGAAAGATA
ACATAGATGAAGTGAAGATTGAAGCTGAAGTTTCCAAACCAACAAACAGATCTGATGACG
TAATAAAAGCAGCATCAATGTTATCCGAGTTACAATCCGGTAAATCATTACTTCCACCAT
CTGCGCCTGCCAATATTGTTACATCACAAACATTAAAACACGTTCATCCGAAGAAAAGAT
TTCGTTTAATTTCTACTGATGCAAGTGGTCATGAGATATCTGAAAGGCTTCGTTCCGATG
ATGAATTATCAGCTATGAGTGACAAAGAAAAAGCAGCTTTGGAAGTTCTCACTGATATGA
AATCAACACCAGAGCGACGAATGTCAACTGTAAATAGATTGTCAAGTTCTGATTCAAGTG
ACCAACCCATCCTCCCAACTACACCTGGTCGTCAACACAGTGAAGTGACGAGTGTCTTCT
CACCACCTCTCACCCCCGCACCATCATCAAGGTCAATATTCAGCCATGATACACACCCAA
GCAGTGACATGCGAATACCTATAACACCCGGCTCTGATACAAATCTTAGTGATCGTAAAA
AGTCTGACAGCAAAGAATTGGAAGCAGTTCAAGCGTTGCTCTCAATAAAAGAGTCCCAAC
CTCCCATCCCTCCCCTGTCTCCTCCCACTCCTGTGAGCACCAAGCATCAACCATTGAAGA
AGAGAGCAGATCTTCGTTTAACTATACCTCCGAAAAGAAGCACTTCTGTGTTGACACAAG
AGGATAAAGATAGGATGACAGCATTAGCTGAGGAGCATAACTACTTTGCAACATCACCAA
GAGTTAAACCAACATCAAGTCACATCCATCCATCTCTGCTTCAAATATTAGAAGAACATA
ACTACAGCTGTCCACCGAGCCAAGCACCAAAAACACCACTGAAAAAATCCCAAGATGAAG
CACCATTCTTACATAATGATGTCATATCAACATCTGAATCTCCGGCATCAGCAGCTGAAC
TTGTGAAACTGCGGCATGGTGATTCAAAGATGTACAAAAAAATTAAACAGAGGACTGACC
AATTATATTATGAGGAGAAAATCAAAAGGTCACTGGTTGGTCGGTTTAGGGAACGCACAC
ATATGGATGATATGAGGATGATGTATAATATCTGGGATAGAGGGCTGGATGTCGAAGATA
TGAAGTATTTACGTCAAGAATATGAGGATATGTTGGCCAACCCTGGTACAGGGGGGTGGG
TGAATGACACACACTGGGTGCCTCACCCTGCTACATACTTCCCTGATGAAAACGATGCTC
TCACCACTTCTCCTGATAAAAGGAACAAAAGGAAAAGAAGGCAGGCACGAAAAGATGATA
TCTCGGATATCAAACCTCATAAAACTGGATGTGCAAGATCTGAAGGTTTTTACAAAGTGA
ACGATAACACGAAGTTGATACAACGGAAGTTAATGTACAGACAAGCTGACAACACACCGC
AACCAAAAGGTCGATCAAAGTACGCAAATGAATCTGCCAGTACATCGGGTGTAGCCACCG
AGAAATCCCGCGAAACGAGGCACATGATGCGACGCATTGCATCTGAATTCGGTTCTGACG
CAAGCGATCTGCTTAAGTATAATCAACTTATGTATCGAAAGAAGAGCGTTAAGTTTAAGC
GAAGTCATATTCATGGTTGGGGTCTTTTTGCCGAGGAAACTATTGGAGCTGACGAAATGG
TCATTGAATATGTTGGCCAACTTGTTCGTTCCCTCATTGCTGATAGAAGAGAGGTTGATT
ATACACGACGTGGTATTGGAAGCTCGTATTTATTCCGCATTGATTCTGACCACATAATTG
ATGCGACGAAATGCGGGAATTTTGCCAGATTTATGAACCATTCATGCAACCCAAGTTGTT
ATGCTAAAGTAATAGCCGTGGACGGGGCAAAGAAGATTGTCATATACTCCAAAGATACAA
TCAAACCAACCGATGAAATAACTTACGATTATAAGTTCCCGATAGAAGACGTTAAAATTC
CTTGTTTCTGTGGCGCACCTAACTGTCGGGGGACGCTTAATTAAATAGCCCCTACCTCTA
AATATTTCTACGAACCTACGGGAGTTTCGAATTAACTATTTCCACCTAAAAAAAGTTACT
CTGTTATAAGAGCAGTATATAGCCTATTTTAGGAATTAATCTGTCTCTTTTTCATCTATA
TTGCCCGAAAGTCAATAGTTTGTTACAATTTTTTACGCTCTGTGGTTGCCGAGTTAAGTT
TCCACCCCTGCATTTTATTATGTCGTTGCTCACTGCTACATTTTGATATTTTTTGCGAGT
TTTGTTGAGCGCTGTAGTAAAACAGGAAGTTTATAAAAAAAAATAGAATGAAAATCGTGT
CAAAATTTAGTTATGAAGGAATAAAAGTTAGTATGTTTGCTTTTAAAT
| PANTHER |
SETD1B (IPR037842) - T[14-187] 5.7E-160 - T[271-749] 5.7E-160 - T[1019-1053] 5.7E-160 - T[1070-1198] 5.7E-160 - T[1286-1848] 5.7E-160 |
| SUPERFAMILY |
RBD_domain_sf (IPR035979) - T[67-161] 3.66E-15 |
| Gene3D |
Nucleotide-bd_a/b_plait_sf (IPR012677) - T[81-187] 1.1E-19 |
| ProSiteProfiles |
RRM_dom (IPR000504) - T[87-165] 10.241 |
| SMART |
RRM_dom (IPR000504) - T[88-161] 1.3E-9 |
| Pfam |
RRM_dom (IPR000504) - T[94-158] 6.0E-9 |
| SMART |
COMPASS_Set1_N-SET (IPR024657) - T[1534-1699] 1.1E-48 |
| Pfam |
COMPASS_Set1_N-SET (IPR024657) - T[1542-1703] 2.8E-26 |
| ProSiteProfiles |
SET_dom (IPR001214) - T[1709-1826] 15.093 |
| SMART |
SET_dom (IPR001214) - T[1709-1832] 3.2E-33 |
| Pfam |
SET_dom (IPR001214) - T[1720-1825] 2.4E-15 |
| SMART |
Post-SET_dom (IPR003616) - T[1832-1848] 5.7E-6 |
| ProSiteProfiles |
Post-SET_dom (IPR003616) - T[1832-1848] 10.51 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| KMT2A_HUMAN | 54.545 % | 169 | 1.02E-41 |
| SET1A_HUMAN | 48.903 % | 309 | 5.23E-85 |
| SET1B_HUMAN | 54.18 % | 315 | 1.14E-86 |