- Transcript 'KH2012:KH.C6.101.v2....'
Transcript Model
Transcript Id
KH2012:KH.C6.101.v2.A.SL3-1
Possible name(s)
AC008695.1; RAPGEF2; RAPGEF6
Gene model
Location
KhC6 [747,700 / 796,030]
Amino acid sequence
Length: 1,902
>KH.C6.101.v2.A.SL3-1
HDWGVENFTRIVVKMSLCSTDPEFVFALRTKGDNRTERELNVIYSRLNRMEILSSMREQS
LRGICTLVRYEKHDANEILYRKDDACRCWYILMSGSVFIQGSMFLPHACFGKQIPGTKRR
GCQCLVLESSEMIAIDYPDMAIHSSGMTSRPHAMLRHDTGHHSPRGALDSVAEVDTSSAE
SSPLHQSRSNSMHKSSNGQIMVGGDNVSQFSKDTEEMDDYSEQDLEEEDSISLHSSSSII
IKDLVIDVLKKDISDRNGDDLEILLEFTKSLQAFSNLTEPIRRALCKVMVFAWVEKAGTV
VLKDNELLDSWSVIINGMYKSVKMGQKKTMGDSFGVQPTLQPQQHNGVMYTMCDDCQFLC
IAQPEYCQVLHQGQENIQNVYNEAGDLVMVKEKREFEGGTKIGNIVIRGNADSLMHHLLE
ENSIDTTYTEDFLLTYRAFNNDPLKISNKLLEWFDSVMFRDKVIRVILLWINNHFNDFEC
DWRMMNVLEKFEEKLHQANLHGQTKLFNIACTAKAQARTVTITRPSSEAELCFQILGGSE
KNFPIYISSVLEGSEGETKGVKRGDLLLEVNGQNFEKLTLEKATAILKKNTELRLTLKTS
LFAFKEMVSELSNPQKKKKHKTDEKNIFFPPGQRGGRMSLTMMSETDAFDQKHKKAGDAV
QSACKEFGITEDLKDYALYRVSVQGEKFVKQSKLPDPLSKLADIPLGSRYYLKNTMNSEQ
LLPDEQIPDLLKEANFSFLDLNCFEVAVFLTRKDYKMFQATASTDFIEDLFHLDAELTQF
KAFEVPAKSNRLFEELQALMDPSRNMSKYRTLLNEMVSQPPVIPYIPVIKKDLTFLDLGN
DTKVEGLINFEKMRMIGKEVRNVCRLCAPDSTQILPSAAAQQRESEKGSQNPIYLTLARR
GRRSSFNNVRRLYEDQINVRRVKQYMQSIEVVSDEDKLMEMSKAVESVIPSASNQQKRRN
TTASLPSDSPSRSSKTLPAFPLRTSSNGSSSSLHSRNNSEPQLAAVPVIALHPTRKKMPV
SSLPKFGANSPQALRKLLSLSEEGGGNDKTGGKKLGTRRNGSVSSHDLSPATSPYMSPKR
REDAQHSVANENINRNNNRLSLPTGVVAEPPSPSIQSAPINSRKFFPPGGSSATSSSRSS
IASASSLGTVSSSNPTHSSLSSLGGSSSPRSSSPVGWGQSGGTTGPQLGPHPSHTHYHQQ
GRTSSSSSADTVKSGAGRHHERPVIKQTRNGRSSSFGGGGMMSSAMMSSIPDRRMNQMSS
STSTPSLSAPGSHQPLILPNHPQMPRTPSIDSGIVSVGSISSDSTRFNPSDDAEIFGRVH
HHPGHQRQHPGRHLDQLHHRINEQSQLSPHLRHGRSNPPPQLEEEDKVEQTFLSGFRGHG
DTPRPDTKVPSNFYPQSVTHVDHGGHPGEPMTIYGHVPPGQSRPMYMMPRNFGKSGVKGI
HDYLICERHAMMRSRQIYANHHITYHRPEPVKTPEALLEDQLVLELQKQRPQLQRHKNSP
ISEDSNLSDKLSKSDPALNVPYPNPYEDPRIRLPPPARTSSPKSMIKQASLPHPSPLSPC
NDNVFSHNHSYHTPNDSRSSFSTPNHSRPHITPPYPQNTPTSTPNTSRNIPTRAEDPSLN
WQYPSRDPPIPRPTTLNTTSPYLNYSAQHGESALQDPITPQYDPHSNQYELYPIPVDMTP
NSSIITTPHLPHSTQVPQHLINGSPGPQLRRKTSQDWNETDLDGEKNQQTMKAWGSSASL
PATPLTSKSNNPQNPLPPHTLQPTLLHGSSISALTVTSKTKKPAPAPPQRTSSFARSRQL
RISSTTSPTSESPPLSPLTPTEHCSLDVSTTCNGWMGNGHVITNGYTPSETRVAPLERRS
LPTYTEAVNQINLKQSRFPAPLNNYRSFNIDAHENTEQVSQV
Nucleotide sequence
Length: 6,182
>KH2012:KH.C6.101.v2.A.SL3-1
ATCCTGAATTTTTCTAAAGTTATATTGCCAAAATATTGAATTCCGATTTTTCTGTCGGGC
TCGTGCATGGGGACCTACAGTGGACTAACATGATTGGGGAGTAGAAAACTTTACACGAAT
AGTTGTGAAAATGTCTCTATGCAGCACGGACCCAGAGTTCGTGTTCGCACTTCGGACCAA
AGGAGACAACCGTACAGAGAGGGAGTTAAATGTCATTTATTCTCGTCTCAATCGAATGGA
AATCCTCTCAAGTATGAGGGAACAAAGTCTCCGCGGTATTTGTACCTTGGTCCGATACGA
AAAACATGACGCAAATGAAATTCTATACAGGAAAGATGATGCGTGCAGATGTTGGTACAT
TCTCATGTCTGGATCAGTCTTCATACAAGGGTCTATGTTTCTACCACATGCGTGCTTTGG
TAAACAAATACCTGGTACAAAACGTAGAGGTTGCCAATGTTTGGTTCTGGAATCTTCTGA
AATGATCGCAATTGATTACCCCGACATGGCAATACACAGCAGTGGAATGACCTCTCGACC
TCATGCCATGCTACGACATGACACCGGACATCATTCGCCACGAGGTGCACTTGACAGCGT
CGCCGAAGTTGACACATCTTCAGCAGAGAGTTCACCCTTACACCAGTCTAGAAGCAACAG
TATGCATAAGTCATCCAATGGTCAAATAATGGTTGGGGGAGACAATGTATCTCAGTTCTC
AAAAGACACAGAAGAGATGGATGATTACTCAGAGCAAGATCTGGAGGAGGAAGATTCCAT
CTCACTTCATTCTTCTTCTTCCATCATCATCAAAGATCTTGTTATCGATGTTTTAAAGAA
AGATATTTCGGATAGAAACGGAGATGATTTAGAAATTCTTCTTGAATTCACAAAAAGCTT
GCAAGCGTTTTCAAATTTAACGGAACCCATACGAAGAGCTTTATGTAAAGTGATGGTTTT
TGCATGGGTGGAAAAAGCTGGCACTGTTGTGCTTAAGGATAACGAATTGCTTGACTCATG
GTCAGTTATAATCAACGGAATGTACAAGTCCGTAAAGATGGGACAGAAGAAGACTATGGG
GGATAGTTTTGGTGTACAACCCACTCTCCAACCTCAGCAGCATAATGGAGTTATGTACAC
AATGTGTGACGATTGTCAGTTCCTGTGCATAGCCCAGCCCGAGTATTGCCAAGTTCTCCA
TCAAGGTCAAGAAAATATACAGAATGTTTATAATGAAGCTGGAGATCTTGTTATGGTGAA
AGAGAAGCGAGAATTTGAAGGCGGAACGAAGATTGGAAACATTGTTATTAGGGGCAATGC
CGACAGTTTAATGCATCACCTGCTCGAAGAGAATTCCATAGACACAACATATACAGAAGA
TTTTCTTCTAACGTACCGTGCTTTTAACAACGACCCGCTGAAAATATCAAACAAATTACT
CGAGTGGTTTGACAGCGTTATGTTTCGAGATAAAGTTATCCGCGTTATACTTCTCTGGAT
AAACAATCATTTCAATGACTTTGAATGTGACTGGCGTATGATGAATGTTCTGGAGAAATT
TGAGGAGAAATTACACCAAGCAAACTTGCATGGACAAACTAAGCTCTTTAACATTGCTTG
TACAGCTAAAGCCCAAGCCAGAACCGTTACAATTACTCGTCCTTCCAGCGAGGCAGAGCT
TTGCTTCCAAATACTTGGGGGGTCTGAGAAAAACTTTCCTATCTACATTTCATCTGTTCT
AGAAGGTTCGGAGGGTGAAACTAAAGGGGTCAAACGAGGTGACTTACTGCTTGAAGTAAA
CGGTCAAAACTTTGAAAAACTAACTCTAGAAAAAGCTACAGCGATTTTGAAGAAAAACAC
AGAATTACGCCTTACTTTGAAAACAAGTTTATTTGCTTTCAAAGAGATGGTCTCAGAACT
GAGTAATCCTCAAAAGAAGAAAAAGCACAAAACGGATGAAAAAAACATCTTTTTCCCTCC
CGGGCAGCGTGGGGGTCGAATGTCTCTCACTATGATGAGTGAAACAGATGCTTTTGACCA
AAAACACAAAAAAGCAGGTGATGCTGTCCAATCGGCTTGCAAAGAGTTTGGCATAACAGA
AGATCTTAAAGACTATGCTTTATACAGGGTGTCAGTACAAGGAGAAAAGTTTGTGAAGCA
ATCTAAACTACCTGATCCACTTTCTAAACTGGCTGATATACCATTAGGCTCAAGATATTA
CTTGAAAAACACGATGAACAGTGAACAGCTCCTACCAGACGAGCAAATACCCGATCTTTT
AAAAGAAGCAAATTTCTCATTTTTAGACCTAAACTGCTTTGAGGTTGCAGTATTTCTGAC
ACGTAAGGATTACAAAATGTTCCAAGCCACGGCTTCTACTGATTTTATTGAAGATCTTTT
CCACCTTGATGCAGAACTTACACAGTTCAAGGCTTTTGAAGTGCCGGCAAAATCAAACCG
TTTATTTGAAGAGCTACAAGCCTTGATGGATCCGTCACGTAATATGTCAAAATACCGAAC
CCTGCTAAATGAGATGGTCTCTCAACCACCAGTGATACCTTATATACCAGTCATTAAAAA
AGATCTCACATTTTTGGACCTCGGTAACGACACAAAGGTGGAAGGATTAATCAACTTTGA
GAAAATGCGAATGATTGGAAAAGAAGTTCGGAACGTGTGTCGTCTCTGTGCACCTGACAG
TACCCAGATTCTACCCAGTGCCGCTGCGCAGCAGAGAGAGTCCGAAAAAGGCAGCCAGAA
CCCTATCTACCTAACCCTGGCCCGCAGAGGACGTAGGTCTTCGTTTAACAATGTAAGAAG
ACTTTACGAGGATCAGATAAACGTACGACGCGTCAAACAATACATGCAGTCAATAGAAGT
CGTTTCCGATGAAGATAAATTAATGGAAATGTCGAAAGCTGTCGAATCTGTTATACCGAG
CGCCTCCAACCAACAAAAACGAAGAAACACAACCGCATCTCTTCCTTCGGACTCCCCATC
AAGATCCTCCAAGACTCTTCCAGCGTTCCCGCTCCGCACATCCTCTAACGGCTCAAGCAG
CAGTCTCCACTCGAGAAATAACTCTGAGCCTCAGCTCGCTGCTGTACCAGTAATAGCCCT
TCATCCAACAAGAAAAAAGATGCCAGTTTCATCGCTCCCAAAATTTGGTGCCAATTCACC
CCAAGCGTTACGAAAGCTTTTATCCCTTTCTGAAGAAGGAGGGGGCAACGACAAAACTGG
GGGTAAAAAACTGGGTACCCGGCGAAATGGGTCAGTCAGCAGTCATGATCTTTCACCCGC
GACTTCACCCTACATGTCACCCAAGCGAAGAGAAGATGCGCAACACTCAGTAGCAAACGA
AAACATCAACAGAAACAACAACAGACTCAGTTTACCAACAGGTGTAGTAGCAGAACCCCC
CTCCCCAAGCATCCAAAGTGCTCCGATAAACTCTCGCAAATTCTTCCCACCGGGCGGCAG
TAGCGCCACATCCAGCTCTCGTTCAAGTATCGCGAGCGCATCTAGTCTCGGGACAGTCTC
GTCTTCAAATCCGACCCATTCGTCACTTTCCTCACTAGGAGGCAGTAGCAGTCCACGGTC
ATCGTCTCCAGTAGGTTGGGGCCAAAGTGGGGGAACCACCGGCCCCCAGTTGGGGCCACA
CCCCTCACACACCCACTATCATCAGCAAGGTCGTACGAGTTCAAGTTCTTCGGCAGATAC
TGTGAAATCAGGAGCTGGTCGCCATCATGAACGCCCTGTTATCAAACAAACACGTAACGG
ACGAAGCAGCTCGTTTGGCGGTGGTGGTATGATGTCATCAGCGATGATGTCATCGATCCC
AGACCGAAGAATGAATCAGATGTCTTCTTCAACTTCCACTCCATCTCTAAGTGCTCCTGG
AAGCCACCAACCACTCATTTTACCCAACCACCCACAAATGCCACGAACACCAAGTATTGA
CAGCGGCATCGTCAGTGTGGGGTCGATTTCATCCGATTCGACGAGATTTAATCCTTCTGA
TGATGCTGAGATCTTTGGGAGAGTCCACCACCATCCAGGACATCAAAGGCAACATCCGGG
AAGACATTTAGATCAGCTGCATCACAGGATCAACGAGCAGAGCCAGCTATCCCCGCATCT
TCGTCACGGAAGATCTAACCCTCCTCCTCAGTTAGAGGAAGAAGACAAAGTAGAACAGAC
TTTTTTATCTGGATTTAGGGGTCATGGGGATACCCCGCGACCAGATACTAAAGTTCCCTC
TAACTTTTACCCCCAATCGGTCACCCACGTTGACCATGGGGGTCACCCAGGTGAACCCAT
GACTATATATGGGCATGTGCCTCCTGGGCAGAGCAGACCAATGTATATGATGCCGCGAAA
CTTCGGCAAAAGCGGCGTTAAAGGCATCCACGATTACTTAATCTGTGAACGGCATGCTAT
GATGAGAAGTCGGCAAATTTACGCGAATCACCATATAACATATCATCGCCCTGAACCAGT
TAAAACACCAGAAGCATTACTAGAGGACCAACTCGTTCTAGAGCTGCAGAAACAACGTCC
ACAACTTCAGCGCCATAAGAACTCTCCGATTTCTGAAGACTCAAATTTATCCGACAAACT
TAGTAAATCGGACCCAGCGTTAAATGTACCCTACCCTAACCCCTATGAAGACCCCCGTAT
ACGTCTACCCCCTCCAGCAAGAACATCATCCCCAAAATCGATGATAAAACAAGCGTCGTT
GCCCCACCCCTCACCCCTATCTCCCTGCAATGACAATGTGTTTTCCCACAACCACTCTTA
CCACACCCCTAACGACTCTAGAAGCTCATTTTCAACCCCCAACCACTCCAGACCCCACAT
AACCCCACCTTACCCCCAAAACACCCCTACCTCTACCCCAAACACTTCACGAAATATACC
CACTCGTGCGGAGGACCCATCCCTTAACTGGCAATACCCTAGTCGTGACCCCCCAATTCC
GAGACCCACTACCTTAAACACGACATCACCCTACCTAAATTACAGTGCCCAGCACGGAGA
AAGCGCGTTACAGGACCCCATAACCCCACAATATGACCCCCATTCAAACCAATACGAATT
ATACCCCATCCCAGTCGACATGACCCCTAATAGCAGTATAATTACCACCCCCCATTTGCC
CCATAGCACCCAAGTACCCCAACATTTGATAAACGGGTCACCAGGTCCACAGTTACGGCG
TAAAACAAGCCAGGATTGGAATGAAACAGATCTAGATGGTGAAAAGAATCAACAGACAAT
GAAAGCTTGGGGCAGCAGTGCCAGTTTACCGGCGACCCCTCTTACTTCAAAGTCAAACAA
CCCCCAAAACCCCCTACCACCCCACACCCTTCAACCCACTTTATTGCATGGGAGTTCTAT
CAGTGCACTGACAGTGACAAGTAAAACAAAGAAACCTGCGCCTGCACCACCACAACGCAC
ATCAAGCTTTGCACGTTCCCGTCAACTTCGTATAAGCTCCACAACAAGTCCAACTTCAGA
GTCACCACCTCTGTCACCCCTAACACCAACCGAGCATTGCTCTCTTGATGTTTCAACCAC
TTGTAATGGTTGGATGGGCAATGGTCATGTGATCACTAATGGCTATACACCATCCGAAAC
TCGTGTTGCACCTTTAGAACGCCGATCGCTCCCGACTTATACAGAAGCTGTCAATCAAAT
AAACTTGAAGCAAAGTCGCTTCCCTGCTCCTTTAAATAACTACAGATCTTTTAATATTGA
TGCACATGAAAACACAGAGCAAGTATCCCAAGTATGACATCATCATCTCATTATGACATC
ATCCCCTTATTAACGTCGCACGCCCTCTTTTCCGAGTTCCATTGCGACGTCGCTTTTTAC
CCCGAGCTGTTTTATCGCTGTTTTAACGCCATTGAAATCTTATTTTGCTGACGTTTGATG
TCTATTATGTTGTGCCTTTATGCGTACTCTTGACTGTGCATTGAATTTTTTCATCTCTTT
TCAAAAGACCCAACTCCCCGCCTTTTGGCTTGTTGCCATGACAACCTGGCTCTCTGCATC
CTCAAGTGACCACCAAGCCATAATAAACAGTGGGGAGTAGATACACCCCCTACAGACCCT
TATAATGAGTTTTTTGTTTAATTATCGCAACCAATTTTATCGCAATCTTTGTTAAATGAA
AG
| Gene3D |
RmlC-like_jellyroll (IPR014710) - T[23-144] 1.0E-13 - T[252-379] 2.8E-40 |
| SUPERFAMILY |
cNMP-bd-like (IPR018490) - T[34-140] 7.46E-11 - T[259-372] 1.7E-10 |
| PANTHER |
RapGEF2 (IPR030739) - T[39-139] 4.4E-230 - T[221-597] 4.4E-230 - T[661-777] 4.4E-230 - T[785-1046] 4.4E-230 |
| CDD |
cNMP-bd_dom (IPR000595) - T[52-143] 3.94083E-6 - T[273-372] 2.21285E-7 |
| SMART |
cNMP-bd_dom (IPR000595) - T[52-162] 2.5 - T[273-388] 1.2E-5 |
| ProSiteProfiles |
cNMP-bd_dom (IPR000595) - T[273-335] 7.169 |
| SUPERFAMILY |
Ras_GEF_dom_sf (IPR023578) - T[400-535] 6.15E-55 - T[724-874] 6.15E-55 - T[917-946] 6.15E-55 |
| ProSiteProfiles |
Ras-like_Gua-exchang_fac_N (IPR000651) - T[402-518] 17.24 |
| SMART |
Ras-like_Gua-exchang_fac_N (IPR000651) - T[402-514] 2.2E-10 |
| Pfam |
Ras-like_Gua-exchang_fac_N (IPR000651) - T[407-491] 5.3E-7 |
| CDD |
Ras-like_Gua-exchang_fac_N (IPR000651) - T[412-497] 4.04584E-13 |
| SUPERFAMILY |
PDZ_sf (IPR036034) - T[516-600] 4.39E-16 |
| ProSiteProfiles |
PDZ (IPR001478) - T[519-589] 14.516 |
| Pfam |
PDZ (IPR001478) - T[520-597] 1.0E-10 |
| SMART |
PDZ (IPR001478) - T[529-601] 1.8E-11 |
| ProSiteProfiles |
RASGEF_cat_dom (IPR001895) - T[663-900] 13.618 |
| SMART |
RASGEF_cat_dom (IPR001895) - T[738-949] 5.6E-7 |
| Pfam |
RASGEF_cat_dom (IPR001895) - T[784-854] 1.0E-15 |
| ProSitePatterns |
Ras_G-nucl-exch_fac_CS (IPR019804) - T[823-852] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| RPGF6_HUMAN | 30.973 % | 172 | 6.12E-43 |
| RPGF2_HUMAN | 52.455 % | 413 | 4.36E-119 |