- Transcript 'KH2012:KH.L170.28.v5...' >
- Transcript 'Boleac.CG.SB_v3.S361...' >
- Transcript 'Harore.CG.MTP2014.S4...' >
- Transcript 'Phmamm.CG.MTP2014.S2...' >
- Transcript 'KH2012:KH.L133.6.v1....'
Transcript Model
Transcript Id
KH2012:KH.L133.6.v1.A.ND1-1
Possible name(s)
ALK; LTK; ROS1
Gene model
Location
KhL133 [35,040 / 45,168]
Amino acid sequence
Length: 728
>KH.L133.6.v1.A.ND1-1
MSPPIPPIVVAIMVGSTIVGCNTSSTSSITCRPYTIHPINVRATTSDSITVGWEQYRPGV
VQIVVSWKLLSNVLGNNWIDSLPLGGSATMDTITDLMSGTGYAMRATYSIEARNRTPPSS
HRRLFGVWKIVKNVSVNGKREWMIGGLTQNVWFQFRVFARNNVGRGDASLTTAPYLFTLP
ASDSRFRWMVIGSSVGSFIFVSIIIFIIACWRCRVLRRRKKKLRHLRDITTIRIDSGMDV
ELARVRHMTNLAMAAANHEGRINLPTDYRDRLPIYPRDQLKLGMLIGSGAFGEVYKGTAA
GISGGEGEASVAVKTLKDGASENEKMEFLMEAYFMSLFDHRNIISLLGVCLDNEPQFLIL
ELMEGGDLLKYLRHARPTQMMSSKLSFLDLIDICLDLSAGCKYLESQHFIHRDLAARNCL
VSSKDYQCRHRVVKIGDFGLARDIYRNDYYLKEGEGLLPVRWMAPESLMMKLYTVQSDVW
SFGVLLWEVMTFGQQPYPEFTNTEVIHFVKEGGRLEQPHGCPEPLYEVMRECWEVEPRDR
PSFNDVLVVLQECKGTCSPNTIPIDPPSTSSINYSLMSPSTDEGFVNGGFTSSDENIVSS
CYAELRIPPPTNQPNVSTHETSQLNYAQLGFSPSRQVSTKNPTSSETSSHYNELPIHKTN
VVVSNLLNTNQYVMSPKLKHEATLDDGRNSNEQFVCETSYNNLNYRCDDEVTNPACETTQ
SHNVITYL
Nucleotide sequence
Length: 3,193
>KH2012:KH.L133.6.v1.A.ND1-1
TTTTAAAGGTCCCACTGAAGTTTCTTCGTTCGAAAAGTTGAATTCTTGTTCCAATATTTC
GTGTGATGTCACTGATGATGTCATCGATGATGCAAGATGTTTGGTGGATGTATCAAACAT
GACAGCGGGATGCCAAATGTTTGAGGAAGGAATTTATATTTGCGGAACTTCATCTGTTTG
GTTTGTTACTTTGACAACTTGTTCTTGTTCTGTTGTTCATCATGACTATGCAGATTTGTC
GTTACTGGATGGGGGTTTGTTTTGGATTGTAAATAATTCAAAGTTATTTCTACGAAACAT
GTCGGTTGTTTCTTCATATTCATCGTCAACGAACAACCCAAATATAGTTTGTCCCATGCT
AATCAACGAGTTGCCATCGGTTACGGATGTTCGTTCTAATTCAATTGTGTTCAATGTATC
GGATATTATGACATCACAACCCAACCATTGTGTTTCATCTACCTCAGTTTATTCGTTTCT
ATACAAACAAACCAACTCAAACTACATTGAACAGTCAACAACATTATTCTCATTCACGGC
AACTTTAATCGGTTTGAACCCAAACGTGAATTACGAGGTTAAATTCACGATACATTGTTT
TTATGCTGACTCATCTTCGCAAGTGATGTCACTTCCTGTTTATATCACCACCAAGTGTAA
AGCACCTCACCCCCCCTCGCAACTTGAATGTCACCCCCGATCCCCCCAATTGTTGTCGCT
ATCATGGTTGGATCCACCATCGTTGGTTGCAACACCTCCAGCACATCCAGCATAACATGC
CGACCTTACACGATCCACCCAATCAATGTTCGAGCTACTACAAGTGACTCCATCACAGTT
GGTTGGGAACAATATCGACCCGGGGTGGTACAGATCGTCGTTTCATGGAAATTACTGTCG
AATGTTCTGGGTAATAATTGGATAGATAGTTTGCCACTGGGTGGCAGCGCAACCATGGAT
ACGATCACAGACCTCATGTCAGGCACCGGGTACGCGATGCGCGCCACTTATTCTATTGAA
GCAAGGAACCGCACCCCACCATCCAGTCACCGTCGGTTGTTCGGGGTTTGGAAGATTGTG
AAGAACGTGAGCGTTAACGGGAAACGTGAATGGATGATTGGAGGCCTCACACAGAACGTG
TGGTTTCAATTCAGGGTTTTTGCTCGAAACAACGTTGGTCGAGGAGACGCAAGCCTCACT
ACCGCCCCCTACCTATTTACACTGCCAGCTAGTGACAGCAGGTTTCGTTGGATGGTGATT
GGGTCCTCGGTTGGAAGTTTCATCTTCGTTTCCATCATCATATTCATCATTGCATGTTGG
CGATGTCGTGTTTTACGACGAAGGAAGAAGAAGTTGCGTCATCTTCGTGACATCACCACG
ATCCGTATCGACTCCGGGATGGACGTCGAACTCGCTCGTGTGCGTCACATGACCAACCTT
GCGATGGCCGCAGCCAACCACGAGGGAAGGATCAACCTCCCAACAGATTACCGCGATCGT
CTCCCTATTTACCCTCGCGACCAACTCAAACTAGGGATGCTGATCGGAAGTGGGGCGTTT
GGTGAGGTTTACAAAGGAACAGCTGCGGGCATTAGTGGGGGGGAGGGGGAGGCATCGGTG
GCCGTTAAAACATTGAAAGACGGGGCGAGTGAGAATGAAAAGATGGAGTTTCTGATGGAA
GCTTACTTCATGAGTTTGTTTGATCATCGCAACATCATATCATTGTTGGGAGTTTGTTTG
GACAACGAACCCCAGTTCCTGATATTGGAGTTGATGGAGGGAGGAGATTTGCTTAAGTAC
CTGAGACACGCTCGTCCTACACAGATGATGTCATCAAAACTATCGTTCCTCGATTTGATT
GACATATGTTTGGACCTAAGCGCGGGGTGTAAATACTTGGAGAGTCAACATTTCATTCAT
AGGGACCTCGCTGCAAGGAATTGTTTGGTTTCGTCGAAAGATTACCAATGTCGCCATCGT
GTGGTGAAGATTGGTGACTTTGGATTGGCCCGAGATATTTATCGGAACGATTATTATTTA
AAGGAGGGGGAGGGGTTGTTGCCCGTCCGCTGGATGGCACCAGAGAGCTTAATGATGAAA
CTGTATACCGTTCAAAGTGATGTGTGGTCGTTTGGAGTTTTGTTATGGGAGGTGATGACA
TTCGGTCAACAACCTTACCCAGAGTTCACTAATACTGAGGTCATCCACTTTGTAAAGGAG
GGGGGAAGGTTGGAGCAACCTCATGGATGTCCTGAACCATTATACGAAGTGATGAGGGAA
TGCTGGGAAGTTGAACCGAGGGATCGACCGTCGTTCAATGATGTGTTGGTGGTTTTGCAG
GAGTGTAAGGGCACATGCTCCCCGAACACCATCCCCATCGACCCCCCATCAACCTCCAGC
ATCAATTACTCCTTGATGTCGCCGAGCACGGACGAAGGTTTCGTTAACGGAGGTTTCACC
TCAAGCGACGAGAACATTGTATCATCATGTTACGCTGAACTAAGAATCCCCCCGCCAACC
AACCAGCCCAATGTTTCAACACACGAGACCTCCCAACTTAACTACGCTCAACTTGGTTTC
TCACCAAGTCGACAAGTAAGCACGAAGAATCCAACCAGCAGCGAAACATCAAGCCATTAC
AACGAACTCCCGATCCACAAAACAAACGTGGTTGTGTCGAATCTTCTTAACACGAACCAA
TACGTGATGAGCCCCAAGTTAAAACACGAAGCTACCTTGGACGATGGAAGGAACAGCAAC
GAACAATTTGTTTGTGAAACTTCTTACAATAATCTTAACTATCGGTGTGATGATGAAGTA
ACGAACCCTGCGTGTGAAACAACTCAAAGTCATAATGTCATCACTTATCTATAAACTTGG
TCAGTGTAAAAGAGGTTACTATCCACCAAGCTACTGTCTGAAACATCTGCTGATCATTAG
TTTAGTATCCAGACAGTAACTTGGTCTATCATCAGTGTAAAAGAGGTTACTATCCACCAA
GTTACTTTTTACCTACACTACATACGTACCATATAAGTTACTTTGCAAGACCTTGCACTT
TACAACATCATGCGTTTTATTAAATGATCATTTTATTAATTGCACAAACTAAGGTGACTT
ATCCATATTTGTTTTTATTTTTTAACAAAACATGTTTGCGGAAACTAACAATACAAAGAA
ATATCTTTTAAAA
| SUPERFAMILY |
FN3_sf (IPR036116) - T[33-172] 4.36E-9 |
| CDD |
FN3_dom (IPR003961) - T[39-119] 0.00539339 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[262-547] 1.5E-79 |
| Pfam |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[280-547] 3.0E-95 |
| SMART |
Tyr_kinase_cat_dom (IPR020635) - T[280-550] 3.3E-134 |
| ProSiteProfiles |
Prot_kinase_dom (IPR000719) - T[280-561] 39.085 |
| ProSitePatterns |
Protein_kinase_ATP_BS (IPR017441) - T[286-314] . |
| PRINTS |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[360-373] 3.6E-37 - T[403-421] 3.6E-37 - T[458-468] 3.6E-37 - T[477-499] 3.6E-37 - T[521-543] 3.6E-37 |
| ProSitePatterns |
Tyr_kinase_AS (IPR008266) - T[409-421] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ROS1_HUMAN | 50.116 % | 389 | 2.78E-117 |
| ALK_HUMAN | 42.571 % | 301 | 1.68E-87 |
| LTK_HUMAN | 49.254 % | 287 | 2.05E-85 |