- Transcript 'Phmamm.CG.MTP2014.S2...' >
- Transcript 'KH2012:KH.L154.1.v1....'
Transcript Model
Transcript Id
KH2012:KH.L154.1.v1.R.ND1-1
Possible name(s)
LRP5; LRP6
Gene model
Location
KhL154 [337,861 / 371,151]
Amino acid sequence
Length: 1,841
>KH.L154.1.v1.R.ND1-1
LNAPFLLLANHVDIRLIPSGEPNNTVIVASDLKGALACDFFFEEQHIYWIDCLNGRIQYV
DMTTPQRKKMDVLVSGMVKPEGLACDWIGRKLYWTDRGTKRIEVSELDGSHRKVLLWNNL
DLPRAIAVDPHNRYMYWTDWGEEPKIERSGMDGSQREVLINQNIYWPNGITLDYEEGKVY
WIEAGHHFIHRINLDGSQREEMFSSNNDNNQLVVPPTSQESSDQSRSSNSTSTNIPLSSE
EGGEWVGALEHPYAITLFRDRVYWSDWRTSSLYSISKNQTEVPRLVKGDILSPMDLQAYN
SQRQKPGPNPCGSTNGGCSHLCLLSPKPPYYKCACPTGVQIMKDRKTCKHGPDQILLLAR
RTDIRMISLDTDDHTDVLLPVKTVLNAVTVDYDPVDKFVYWTDEDRKAILRCHLNGTGSE
AIITENLEQSDGMAIDWVARNLYWTDTGRNYVAVARLNGTSRRILIETEIDEPRAIVVDP
TAGYFYWTDWGENPKIERVEMDGTNRILFVRKHLKWPNGLAIDHTHGWLYWADASLDKIE
RIKLDGTQRKMLVSGKIPHIFGFSILGNYLYWADWQRRRIERMRIGDPRSREILIDQLPN
LMGVKATGMTPLPGTNPCARNNGGCSHLCLYTPEGPRCSCPTGLELAINSHQCVVPEAYL
LYSLPKVGGIKEISLDTAQNDKSLPFNKPVEAYLLDFSVDDSMVYWTNTRDMTISRAFMN
GSNVERFIDIGIEILQGVAVDWIGRNVFWADAQANRIEVARMDGTSRRPIIWQGLDSPAC
IAMDPANGYIYWSEWGTDTCIKRANLDGSNVVRLTQIGDVGRASSLTIDYEDRRIYWVDY
DSNMIMSSDMEGRNLIEVINVADEPGNVISSLTLYGEHVYWADSKQKTIQRANKLHGASR
RIIETGLGSIDDMLVFHASRQIGVTSCSRDNGGCQYLCLSLPGGNYTCECPAHYTLNLLD
NSSCVAPLNFLLVSQTSYISRIVFESSEGVLGVIPGAEIDQRAVYDENAKPTPDAVLPIK
GLKDACSIDYDPIERTIYWIDCATGEIKSCRDNGTDARVLVANRGSNGSNRPHDLAVEPY
TRHLYWTDSLSNSIQMMNLNGTMIGTVLSGKLNAQGVGNGKYIDIMPRKITIDSMKGRIY
FSNTCHDTKSCRFKILQSALDGSDCIELFSHNLHNVSAMVVDSQSKRLYWSDPDREVIEW
SNTDGSHRTTLIENSISQPVGLAVFGDSIYWVDSQVHILTNKIDGSNRRIIQSRVRNLKA
IAAAKLINLGDRLQHPCFTDNGGCSHICVPQVTGVTRCSCPTHLAVIEDSKCGKPVTCGP
GYFRCKTLSICIPMNWKCDSENDCEDASDEMNCETNRLPCKDYEVECKAVLPQCVNQSKI
CDGTYDCISQSDEMNCDCGPNLKVCPSGQCVAVGSSCDCTNCQPIIGGNDQDNSMVIVIG
IVCGCVVLLGIGLFIRHCMTHNSRYPQGVVMFAPHTNGNCTVNVEIQSRADTTEVVNHQK
TNGNQSRKKGSTKGKASINLSFHPSGSRSGSNSRFGVPSNWQFPVHYTKDCHSMDRPCVP
GASRCSSIQAKVFSPTTNPPPSPATVRSGSKSGDRVYSTDSGRSHHRCKNGYKHRRSQHR
YPIHHPPPPTPCNTDTCDDVDRGYRHGGSNRSPPSTNSSVPHEPPPPYHHHQCCYHCYHQ
YPPQCRHPDGSSSSSYQCEDDDCSCGGDSLPSYPPSYNQRGRSWRRPPHRSYLSSDLNSD
SDPFAPPPTPRSQYMSECCYTHGETTEADDPLDEEDETVDDDVTNDVTENLIAGSGVTED
EEGGSEDDADTVLLNPRSSPSVTERSFRIYNPPPSPATDSS
Nucleotide sequence
Length: 6,504
>KH2012:KH.L154.1.v1.R.ND1-1
CTCTCAACGCCCCTTTTTTATTGCTCGCAAATCATGTTGATATTCGATTAATTCCATCTG
GTGAGCCCAACAACACAGTTATCGTGGCTTCAGACTTAAAAGGAGCATTAGCCTGTGATT
TCTTCTTTGAGGAACAGCATATCTACTGGATTGACTGTCTTAATGGAAGGATCCAGTACG
TTGACATGACGACCCCACAGCGCAAAAAAATGGACGTACTTGTTTCGGGTATGGTTAAAC
CTGAAGGCCTCGCATGCGACTGGATCGGTCGAAAACTGTACTGGACAGACCGTGGAACAA
AAAGAATTGAAGTTAGTGAATTAGATGGAAGTCACAGGAAAGTTTTACTGTGGAACAATC
TAGACCTTCCGAGAGCTATAGCAGTGGATCCTCATAACAGGTACATGTACTGGACAGACT
GGGGCGAAGAGCCGAAGATAGAACGTTCTGGAATGGATGGTTCACAGAGAGAAGTTCTGA
TCAACCAGAATATTTACTGGCCTAATGGAATCACACTTGATTATGAAGAAGGGAAAGTTT
ACTGGATCGAAGCTGGCCATCATTTTATTCATCGTATTAACTTAGATGGCTCACAGAGAG
AAGAGATGTTCAGCAGTAACAACGACAACAACCAGCTCGTTGTTCCTCCAACGTCCCAGG
AGTCAAGCGATCAGAGTCGCTCCTCTAACTCTACATCCACGAACATCCCTCTCTCCTCCG
AGGAGGGAGGAGAGTGGGTGGGAGCTCTGGAGCATCCCTACGCGATCACTCTCTTCCGGG
ATCGAGTTTACTGGTCCGATTGGAGGACCTCATCTCTTTATTCCATCTCGAAAAATCAAA
CCGAGGTTCCTCGTTTAGTGAAAGGGGACATCCTGTCGCCAATGGACCTACAGGCCTATA
ACTCGCAGAGGCAAAAACCAGGTCCTAATCCGTGTGGTTCCACGAATGGTGGATGCTCAC
ACTTATGTCTCCTCTCACCCAAGCCCCCATATTACAAGTGTGCGTGCCCGACCGGGGTCC
AAATCATGAAGGACCGAAAAACATGTAAACACGGTCCAGACCAGATCCTTCTGCTTGCAC
GAAGAACAGACATTCGAATGATTTCGCTCGACACTGATGACCATACGGATGTACTACTGC
CTGTAAAGACAGTGCTGAATGCAGTCACAGTGGATTACGACCCAGTGGATAAGTTTGTGT
ACTGGACGGATGAAGACAGAAAAGCAATTCTCAGATGTCATCTTAACGGCACAGGTTCTG
AAGCAATTATCACAGAAAACTTGGAGCAGTCGGATGGCATGGCAATAGATTGGGTTGCAA
GGAACTTGTATTGGACAGATACGGGTAGAAACTATGTAGCAGTGGCACGGCTTAATGGGA
CATCCCGGAGAATTCTTATCGAAACTGAGATTGACGAACCAAGAGCAATCGTGGTCGATC
CAACTGCTGGCTATTTCTACTGGACCGACTGGGGAGAAAACCCCAAGATAGAACGTGTCG
AAATGGACGGCACAAACAGAATTTTGTTCGTAAGAAAACACCTAAAATGGCCAAACGGTT
TAGCAATTGACCACACCCATGGCTGGCTGTATTGGGCCGACGCATCGCTCGATAAAATTG
AGCGGATCAAGCTTGACGGGACACAGAGGAAGATGTTGGTGTCCGGGAAGATACCACACA
TATTTGGATTCAGCATTCTTGGCAACTATCTCTACTGGGCTGACTGGCAAAGAAGAAGAA
TTGAACGAATGCGAATTGGTGATCCGAGATCCAGGGAAATACTCATAGATCAACTTCCTA
ACCTAATGGGGGTGAAGGCCACTGGTATGACACCTTTACCAGGAACTAATCCTTGTGCAA
GAAATAACGGGGGTTGCTCACATTTGTGTCTATATACACCAGAGGGTCCGAGGTGCAGTT
GCCCAACTGGTCTCGAATTAGCGATCAACAGTCACCAGTGCGTGGTACCTGAAGCTTACC
TTCTCTATTCACTACCAAAAGTTGGCGGAATTAAAGAGATTTCTCTCGACACTGCACAAA
ACGACAAGTCCCTTCCATTCAACAAACCCGTTGAAGCTTACTTACTTGATTTCTCAGTAG
ATGATAGTATGGTGTATTGGACAAATACAAGAGACATGACAATCTCGCGTGCTTTTATGA
ACGGGTCCAACGTTGAGAGATTCATAGATATCGGCATAGAGATCTTACAAGGGGTCGCGG
TTGACTGGATCGGACGCAATGTGTTCTGGGCTGACGCTCAAGCCAATCGGATCGAAGTTG
CTCGTATGGACGGGACAAGCAGGCGACCAATCATATGGCAGGGATTGGATTCACCTGCGT
GTATCGCCATGGATCCAGCCAATGGGTACATATACTGGTCAGAGTGGGGCACAGACACGT
GCATAAAACGCGCAAATCTGGATGGTTCCAACGTGGTACGATTGACACAAATCGGGGACG
TTGGACGCGCTAGTTCCCTTACTATAGATTACGAGGATAGAAGGATTTATTGGGTGGATT
ATGACAGTAATATGATCATGTCTTCCGATATGGAAGGCAGAAACTTGATTGAAGTAATCA
ATGTAGCTGACGAACCAGGAAATGTTATTTCAAGTTTAACATTATATGGAGAACATGTGT
ATTGGGCAGATAGCAAACAGAAGACCATACAAAGAGCAAATAAATTGCACGGAGCGAGCA
GGAGAATAATCGAGACTGGTCTCGGTTCTATTGATGATATGTTGGTGTTTCACGCATCAC
GTCAAATCGGTGTCACATCATGTTCACGTGATAACGGGGGGTGCCAATACCTATGTTTAA
GTCTTCCAGGGGGAAACTACACTTGCGAGTGCCCTGCCCATTACACGTTAAATCTATTGG
ATAATTCTTCATGTGTTGCCCCATTAAATTTCCTATTGGTGAGCCAGACTTCATATATTT
CCCGTATTGTGTTCGAATCCTCCGAAGGGGTCCTAGGGGTAATTCCCGGGGCTGAGATTG
ACCAGCGAGCAGTTTACGACGAGAATGCAAAACCAACGCCTGACGCCGTGTTACCCATTA
AAGGGCTGAAGGATGCCTGCTCAATTGACTACGACCCAATAGAACGCACAATATACTGGA
TCGACTGCGCCACCGGTGAAATAAAGAGTTGCCGAGACAATGGCACAGATGCGAGAGTTC
TCGTCGCAAATAGGGGTTCAAACGGGTCAAATCGACCCCATGATTTAGCTGTGGAACCCT
ACACAAGACATTTGTACTGGACAGACTCTCTGTCTAATTCCATCCAAATGATGAATTTAA
ATGGGACCATGATTGGGACTGTATTATCTGGTAAACTCAATGCACAAGGGGTGGGAAATG
GAAAATACATTGATATTATGCCAAGGAAAATTACAATAGACTCCATGAAAGGGCGCATAT
ACTTCAGTAACACATGCCATGACACAAAGTCATGCAGATTTAAGATTCTACAATCTGCTT
TAGACGGATCTGATTGCATTGAATTATTCAGTCATAATTTACACAACGTTTCAGCTATGG
TAGTAGACTCACAATCTAAAAGATTATACTGGTCTGATCCGGATCGTGAGGTTATAGAAT
GGTCAAATACCGATGGAAGCCATCGTACCACGCTTATTGAGAACAGTATAAGTCAACCAG
TTGGTTTAGCTGTGTTTGGTGATTCCATCTATTGGGTGGACTCTCAGGTTCATATTTTAA
CGAATAAAATCGACGGTTCAAATCGACGAATTATTCAAAGTCGAGTCCGAAACTTAAAAG
CGATCGCTGCAGCCAAGCTTATCAATCTTGGTGACCGATTACAACACCCATGTTTCACTG
ATAATGGGGGTTGTTCACATATCTGCGTGCCACAAGTTACCGGGGTGACACGGTGTTCGT
GCCCCACACATCTTGCTGTGATAGAAGATTCCAAATGTGGCAAGCCAGTGACGTGTGGTC
CAGGTTATTTTCGATGCAAAACTTTATCGATTTGTATTCCCATGAATTGGAAATGTGACA
GTGAGAATGATTGCGAAGATGCCTCAGATGAAATGAATTGTGAGACAAATAGACTGCCGT
GTAAGGATTACGAAGTGGAATGCAAAGCAGTCTTGCCCCAGTGCGTCAACCAGTCAAAAA
TTTGCGACGGAACGTATGATTGCATCTCGCAAAGTGATGAAATGAATTGCGATTGTGGAC
CTAACCTAAAGGTGTGTCCATCTGGCCAGTGTGTGGCAGTAGGGAGCTCATGTGACTGCA
CCAACTGTCAGCCAATCATTGGCGGCAATGATCAAGACAACTCAATGGTTATAGTGATCG
GCATCGTATGTGGGTGCGTGGTTTTGCTCGGAATCGGTCTTTTTATACGACATTGCATGA
CCCACAACTCTCGTTACCCGCAAGGGGTTGTCATGTTCGCCCCGCACACGAACGGCAACT
GCACCGTCAACGTAGAAATCCAGTCGCGTGCCGACACAACTGAAGTCGTAAACCACCAAA
AAACTAACGGCAACCAGAGCCGTAAAAAGGGGTCAACAAAGGGGAAAGCATCGATTAACC
TTTCCTTTCACCCCAGCGGGAGTAGATCGGGGTCAAATTCCCGGTTTGGGGTCCCATCAA
ATTGGCAATTTCCCGTCCATTATACAAAGGATTGCCATTCTATGGATCGTCCCTGTGTTC
CAGGGGCATCAAGGTGTTCAAGCATACAAGCCAAGGTTTTCTCACCGACCACCAACCCCC
CACCCTCCCCTGCAACAGTGAGATCGGGCTCCAAAAGCGGGGACAGGGTTTATTCAACTG
ATTCTGGAAGGTCTCACCATAGATGTAAGAATGGATATAAACACAGAAGGTCTCAGCACC
GCTACCCAATCCATCACCCTCCACCCCCTACCCCATGCAACACAGACACATGCGATGACG
TAGACCGGGGTTACAGACACGGGGGTTCGAATCGAAGCCCCCCATCAACGAACTCAAGCG
TCCCGCATGAGCCCCCGCCCCCCTACCACCACCATCAGTGTTGTTACCACTGCTACCATC
AATACCCCCCACAATGTAGACACCCAGATGGCAGCTCGTCAAGCTCGTACCAATGTGAGG
ACGACGATTGCTCCTGTGGTGGTGACTCCCTACCATCTTACCCCCCCTCTTATAATCAGC
GGGGGCGCTCCTGGCGAAGACCTCCACATCGCTCCTACCTCTCATCGGATCTGAATTCGG
ATTCGGATCCATTCGCGCCCCCGCCAACCCCACGCAGCCAGTACATGTCGGAATGTTGTT
ACACCCACGGTGAAACGACGGAGGCCGACGATCCATTAGACGAAGAAGATGAGACGGTTG
ATGATGATGTCACTAATGACGTCACAGAAAACCTCATTGCAGGATCGGGAGTCACGGAAG
ATGAGGAGGGAGGATCTGAAGATGATGCGGACACAGTTTTACTCAATCCGAGGTCATCCC
CATCAGTAACGGAGCGAAGTTTTCGCATCTATAACCCTCCGCCATCCCCAGCCACAGATT
CCTCATGAAGCAGTGCTGCCAGTTGAAAAACTTAATACAAAAAATAGTGCTCCCAGTTAA
AAACCTCTGCACAAAAGGCAGTGCTGCCAGTTGAAAAACTCGGTACAAAAAACAGTGCTG
TCAGTTGAAAAACTTGTCACAAAAAGCAGTGCTACCAGTTGAAAAACTTGTCATAAAAAG
CAGTGCTCCCAGTTAAAAAACTTGACACAAAAAACAGTACTACCAGTTGAAAAACTTGTC
ACAAAAGCAGTGCTCCCAGTTAAATAACTCCTCACAAAAAACAGTGCTACCAGTTAAAAG
GTCAGAAAATGCCAGGCGAATAACTAAAACATGATCGAACAGCACTGCAGAAACATGTAT
ATAAATCCAATTCCCTATTGTAATGGGAATGTTTAATGTTTTTACCATTTTTTGTTTTAT
TTCATTTCAAAACCAATAGAACCCTCTGCCAACGCTGTCGTTGCCAACTTTTTTGCATTT
TATTCTTTTTTTTGTTTGTTATCAAATTTTCAGCGGTACACGAAACTTTGCATTTGATCT
TGTATATACTGCACTTCAATTCTTCCGAACGAATCATGTTTTTTTTATTGTACAGTATAA
ACATTAAGTTTGTCTGTCGTTCTGGTCAACTATCTTGACAAAATAATCGCATAAACGTTT
TAGGATTTTCAGGTACACTTTTACATTTCTTAGAATTTTAAAGTTTGCAGTGGTAGCCTT
TGAGTTTTTTTACGACGAAAAAAAACACTTTTTTTCGTTTTTTTTACCGCCGTTTTATGC
GTGCCAATTCTATTCTATTTCTATTTTCTGTAGAATAGAATGCGTGCCAATTATTCATAT
AAGCATGAGCCTTTTTAAATTAATTTTTTTGTAAAGTGTACATCAGTCTTCTTACCTCTC
TGGTCATTGTTCTAGTGCCTGGTTATCATGTCTGAACGATTTGCAATTGCCCAACGAATG
TAAATAAATTTGGTTTTAACTATT
| Gene3D |
6-blade_b-propeller_TolB-like (IPR011042) - T[2-214] 1.0E-78 - T[218-337] 7.2E-26 - T[340-654] 1.2E-124 - T[655-952] 5.3E-91 - T[953-1316] 4.2E-78 |
| SMART |
LDLR_classB_rpt (IPR000033) - T[25-67] 5.4 - T[70-112] 2.5E-12 - T[113-156] 3.6E-15 - T[157-199] 3.2E-13 - T[235-282] 2.1 - T[377-419] 0.0014 - T[420-462] 3.1E-12 - T[463-506] 3.3E-15 - T[507-549] 1.6E-13 - T[550-590] 2.2E-4 - T[682-724] 8.4 - T[725-767] 1.0E-9 - T[768-811] 4.1E-10 - T[813-855] 3.3E-5 - T[859-900] 9.8 - T[1015-1057] 0.24 - T[1058-1104] 7.3E-7 - T[1166-1208] 4.9E-7 - T[1209-1248] 3.8E-4 |
| ProSiteProfiles |
LDLR_classB_rpt (IPR000033) - T[45-89] 9.831 - T[90-132] 17.326 - T[133-176] 16.909 - T[177-218] 9.576 - T[260-302] 8.833 - T[397-439] 14.147 - T[440-482] 15.888 - T[483-526] 16.143 - T[527-569] 13.358 - T[570-610] 6.42 - T[702-744] 11.688 - T[745-787] 14.704 - T[788-832] 11.711 - T[833-860] 8.578 - T[877-919] 8.764 - T[1035-1081] 10.736 - T[1082-1112] 8.485 - T[1137-1185] 6.606 - T[1186-1228] 15.099 - T[1229-1251] 5.794 |
| Pfam |
LDLR_classB_rpt (IPR000033) - T[90-130] 1.5E-11 - T[133-174] 5.1E-15 - T[440-480] 7.8E-11 - T[484-524] 6.4E-10 - T[529-555] 1.2E-5 - T[745-785] 2.2E-5 - T[788-830] 7.2E-5 - T[1187-1225] 1.3E-5 |
| SMART |
EGF-like_dom (IPR000742) - T[310-349] 17.0 - T[617-654] 0.035 - T[926-965] 0.03 - T[1276-1313] 56.0 |
| SUPERFAMILY |
LDL_receptor-like_sf (IPR036055) - T[1316-1353] 8.25E-10 - T[1358-1396] 4.32E-6 |
| ProSiteProfiles |
LDrepeatLR_classA_rpt (IPR002172) - T[1317-1354] 13.413 - T[1359-1397] 10.938 |
| SMART |
LDrepeatLR_classA_rpt (IPR002172) - T[1317-1355] 2.4E-14 - T[1359-1398] 7.9E-4 |
| Pfam |
LDrepeatLR_classA_rpt (IPR002172) - T[1317-1353] 8.3E-12 - T[1359-1396] 5.4E-6 |
| CDD |
LDrepeatLR_classA_rpt (IPR002172) - T[1318-1353] 2.89862E-11 - T[1360-1396] 6.27557E-5 |
| PRINTS |
LDrepeatLR_classA_rpt (IPR002172) - T[1329-1350] 1.1E-9 - T[1372-1393] 1.1E-9 |
| ProSitePatterns |
LDLR_class-A_CS (IPR023415) - T[1331-1353] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| LRP4_HUMAN | 34.736 % | 813 | 0 |
| LRP6_HUMAN | 42.771 % | 1331 | 0 |
| LRP5_HUMAN | 42.895 % | 1254 | 0 |