- Transcript 'KH2012:KH.L154.1.v1....' >
- Transcript 'Cisavi.CG.ENS81.R132...' >
- Transcript 'Phmamm.CG.MTP2014.S2...' >
- Transcript 'Cisavi.CG.ENS81.R54....' >
- Transcript 'KH2012:KH.L154.1.v3....'
Transcript Model
Transcript Id
KH2012:KH.L154.1.v3.A.SL2-1
Possible name(s)
LRP5; LRP6
Gene model
Location
KhL154 [337,861 / 372,434]
Amino acid sequence
Length: 1,842
>KH.L154.1.v3.A.SL2-1
YKMKLLFISFLYFLSSNASKDTALNAPFLLLANHVDIRLIPSGEPNNTVIVASDLKGALA
CDFFFEEQHIYWIDCLNGRIQYVDMTTPQRKKMDVLVSGMVKPEGLACDWIGRKLYWTDR
GTKRIEVSELDGSHRKVLLWNNLDLPRAIAVDPHNRYMYWTDWGEEPKIERSGMDGSQRE
VLINQNIYWPNGITLDYEEGKVYWIEAGHHFIHRINLDGSQSDQSRSSNSTSTNIPLSSE
EGGEWVGALEHPYAITLFRDRVYWSDWRTSSLYSISKNQTEVPRLVKGDILSPMDLQAYN
SQRQKPGPNPCGSTNGGCSHLCLLSPKPPYYKCACPTGVQIMKDRKTCKHGPDQILLLAR
RTDIRMISLDTDDHTDVLLPVKTVLNAVTVDYDPVDKFVYWTDEDRKAILRCHLNGTGSE
AIITENLEQSDGMAIDWVARNLYWTDTGRNYVAVARLNGTSRRILIETEIDEPRAIVVDP
TAGYFYWTDWGENPKIERVEMDGTNRILFVRKHLKWPNGLAIDHTHGWLYWADASLDKIE
RIKLDGTQRKMLVSGKIPHIFGFSILGNYLYWADWQRRRIERMRIGDPRSREILIDQLPN
LMGVKATGMTPLPGTNPCARNNGGCSHLCLYTPEGPRCSCPTGLELAINSHQCVVPEAYL
LYSLPKVGGIKEISLDTAQNDKSLPFNKPVEAYLLDFSVDDSMVYWTNTRDMTISRAFMN
GSNVERFIDIGIEILQGVAVDWIGRNVFWADAQANRIEVARMDGTSRRPIIWQGLDSPAC
IAMDPANGYIYWSEWGTDTCIKRANLDGSNVVRLTQIGDVGRASSLTIDYEDRRIYWVDY
DSNMIMSSDMEGRYLINVADEPGNVISSLTLYGEHVYWADSKQKTIQRANKLHGASRRII
ETGLGSIDDMLVFHASRQIGVTSCSRDNGGCQYLCLSLPGGNYTCECPAHYTLNLLDNSS
CVAPLNFLLVSQTSYISRIVFESSEGVLGVIPGAEIDQRAVYDENAKPTPDAVLPIKGLK
DACSIDYDPIERTIYWIDCATGEIKSCRDNGTDARVLVANRGSNGSNRPHDLAVEPYTRH
LYWTDSLSNSIQMMNLNGTMIGTVLSGKLNAQGVGNGKYIDIMPRKITIDSMKGRIYFSN
TCHDTKSCRFKILQSALDGSDCIELFSHNLHNVSAMVVDSQSKRLYWSDPDREVIEWSNT
DGSHRTTLIENSISQPVGLAVFGDSIYWVDSQVHILTNKIDGSNRRIIQSRVRNLKAIAA
AKLINLGDRLQHPCFTDNGGCSHICVPQVTGVTRCSCPTHLAVIEDSKCGKPVTCGPGYF
RCKTLSICIPMNWKCDSENDCEDASDEMNCETNRLPCKDYEVECKAVLPQCVNQSKICDG
TYDCISQSDEMNCAFSLDCGPNLKVCPSGQCVAVGSSCDCTNCQPIIGGNDQDNSMVIVI
GIVCGCVVLLGIGLFIRHCMTHNSRYPQGVVMFAPHTNGNCTVNVEIQSRADTTEVVNHQ
KTNGNQSRKKGSTKGKASINLSFHPSGSRSGSNSRFGVPSNWQFPVHYTKDCHSMDRPCV
PGASRCSSIQAKVFSPTTNPPPSPATVRSGSKSGDRVYSTDSGRSHHRCKNGYKHRRSQH
RYPIHHPPPPTPCNTDTCDDVDRGYRHGGSNRSPPSTNSSVPHEPPPPYHHHQCCYHCYH
QYPPQCRHPDGSSSSSYQCEDDDCSCGGDSLPSYPPSYNQRGRSWRRPPHRSYLSSDLNS
DSDPFAPPPTPRSQYMSECCYTHGETTEADDPLDEEDETVDDDVTNDVTENLIAGSGVTE
DEEGGSEDDADTVLLNPRSSPSVTERSFRIYNPPPSPATDSS
Nucleotide sequence
Length: 6,619
>KH2012:KH.L154.1.v3.A.SL2-1
GCTGTTAAGTTAAAGCTGTATGATGTGTTAAGGAGGCGCACACTATGACATTGGATTTTA
TTTTACACGTTAAACGACGGAAAAGGGATTTTAATGAGAGAGAATAACATTTAATATAAA
ATGAAGCTGCTTTTTATTTCTTTTTTATACTTTTTATCATCAAATGCAAGTAAAGATACT
GCTCTCAACGCCCCTTTTTTATTGCTCGCAAATCATGTTGATATTCGATTAATTCCATCT
GGTGAGCCCAACAACACAGTTATCGTGGCTTCAGACTTAAAAGGAGCATTAGCCTGTGAT
TTCTTCTTTGAGGAACAGCATATCTACTGGATTGACTGTCTTAATGGAAGGATCCAGTAC
GTTGACATGACGACCCCACAGCGCAAAAAAATGGACGTACTTGTTTCGGGTATGGTTAAA
CCTGAAGGCCTCGCATGCGACTGGATCGGTCGAAAACTGTACTGGACAGACCGTGGAACA
AAAAGAATTGAAGTTAGTGAATTAGATGGAAGTCACAGGAAAGTTTTACTGTGGAACAAT
CTAGACCTTCCGAGAGCTATAGCAGTGGATCCTCATAACAGGTACATGTACTGGACAGAC
TGGGGCGAAGAGCCGAAGATAGAACGTTCTGGAATGGATGGTTCACAGAGAGAAGTTCTG
ATCAACCAGAATATTTACTGGCCTAATGGAATCACACTTGATTATGAAGAAGGGAAAGTT
TACTGGATCGAAGCTGGCCATCATTTTATTCATCGTATTAACTTAGATGGCTCACAGAGC
GATCAGAGTCGCTCCTCTAACTCTACATCCACGAACATCCCTCTCTCCTCCGAGGAGGGA
GGAGAGTGGGTGGGAGCTCTGGAGCATCCCTACGCGATCACTCTCTTCCGGGATCGAGTT
TACTGGTCCGATTGGAGGACCTCATCTCTTTATTCCATCTCGAAAAATCAAACCGAGGTT
CCTCGTTTAGTGAAAGGGGACATCCTGTCGCCAATGGACCTACAGGCCTATAACTCGCAG
AGGCAAAAACCAGGTCCTAATCCGTGTGGTTCCACGAATGGTGGATGCTCACACTTATGT
CTCCTCTCACCCAAGCCCCCATATTACAAGTGTGCGTGCCCGACCGGGGTCCAAATCATG
AAGGACCGAAAAACATGTAAACACGGTCCAGACCAGATCCTTCTGCTTGCACGAAGAACA
GACATTCGAATGATTTCGCTCGACACTGATGACCATACGGATGTACTACTGCCTGTAAAG
ACAGTGCTGAATGCAGTCACAGTGGATTACGACCCAGTGGATAAGTTTGTGTACTGGACG
GATGAAGACAGAAAAGCAATTCTCAGATGTCATCTTAACGGCACAGGTTCTGAAGCAATT
ATCACAGAAAACTTGGAGCAGTCGGATGGCATGGCAATAGATTGGGTTGCAAGGAACTTG
TATTGGACAGATACGGGTAGAAACTATGTAGCAGTGGCACGGCTTAATGGGACATCCCGG
AGAATTCTTATCGAAACTGAGATTGACGAACCAAGAGCAATCGTGGTCGATCCAACTGCT
GGCTATTTCTACTGGACCGACTGGGGAGAAAACCCCAAGATAGAACGTGTCGAAATGGAC
GGCACAAACAGAATTTTGTTCGTAAGAAAACACCTAAAATGGCCAAACGGTTTAGCAATT
GACCACACCCATGGCTGGCTGTATTGGGCCGACGCATCGCTCGATAAAATTGAGCGGATC
AAGCTTGACGGGACACAGAGGAAGATGTTGGTGTCCGGGAAGATACCACACATATTTGGA
TTCAGCATTCTTGGCAACTATCTCTACTGGGCTGACTGGCAAAGAAGAAGAATTGAACGA
ATGCGAATTGGTGATCCGAGATCCAGGGAAATACTCATAGATCAACTTCCTAACCTAATG
GGGGTGAAGGCCACTGGTATGACACCTTTACCAGGAACTAATCCTTGTGCAAGAAATAAC
GGGGGTTGCTCACATTTGTGTCTATATACACCAGAGGGTCCGAGGTGCAGTTGCCCAACT
GGTCTCGAATTAGCGATCAACAGTCACCAGTGCGTGGTACCTGAAGCTTACCTTCTCTAT
TCACTACCAAAAGTTGGCGGAATTAAAGAGATTTCTCTCGACACTGCACAAAACGACAAG
TCCCTTCCATTCAACAAACCCGTTGAAGCTTACTTACTTGATTTCTCAGTAGATGATAGT
ATGGTGTATTGGACAAATACAAGAGACATGACAATCTCGCGTGCTTTTATGAACGGGTCC
AACGTTGAGAGATTCATAGATATCGGCATAGAGATCTTACAAGGGGTCGCGGTTGACTGG
ATCGGACGCAATGTGTTCTGGGCTGACGCTCAAGCCAATCGGATCGAAGTTGCTCGTATG
GACGGGACAAGCAGGCGACCAATCATATGGCAGGGATTGGATTCACCTGCGTGTATCGCC
ATGGATCCAGCCAATGGGTACATATACTGGTCAGAGTGGGGCACAGACACGTGCATAAAA
CGCGCAAATCTGGATGGTTCCAACGTGGTACGATTGACACAAATCGGGGACGTTGGACGC
GCTAGTTCCCTTACTATAGATTACGAGGATAGAAGGATTTATTGGGTGGATTATGACAGT
AATATGATCATGTCTTCCGATATGGAAGGTAGGTATTTAATCAATGTAGCTGACGAACCA
GGAAATGTTATTTCAAGTTTAACATTATATGGAGAACATGTGTATTGGGCAGATAGCAAA
CAGAAGACCATACAAAGAGCAAATAAATTGCACGGAGCGAGCAGGAGAATAATCGAGACT
GGTCTCGGTTCTATTGATGATATGTTGGTGTTTCACGCATCACGTCAAATCGGTGTCACA
TCATGTTCACGTGATAACGGGGGGTGCCAATACCTATGTTTAAGTCTTCCAGGGGGAAAC
TACACTTGCGAGTGCCCTGCCCATTACACGTTAAATCTATTGGATAATTCTTCATGTGTT
GCCCCATTAAATTTCCTATTGGTGAGCCAGACTTCATATATTTCCCGTATTGTGTTCGAA
TCCTCCGAAGGGGTCCTAGGGGTAATTCCCGGGGCTGAGATTGACCAGCGAGCAGTTTAC
GACGAGAATGCAAAACCAACGCCTGACGCCGTGTTACCCATTAAAGGGCTGAAGGATGCC
TGCTCAATTGACTACGACCCAATAGAACGCACAATATACTGGATCGACTGCGCCACCGGT
GAAATAAAGAGTTGCCGAGACAATGGCACAGATGCGAGAGTTCTCGTCGCAAATAGGGGT
TCAAACGGGTCAAATCGACCCCATGATTTAGCTGTGGAACCCTACACAAGACATTTGTAC
TGGACAGACTCTCTGTCTAATTCCATCCAAATGATGAATTTAAATGGGACCATGATTGGG
ACTGTATTATCTGGTAAACTCAATGCACAAGGGGTGGGAAATGGAAAATACATTGATATT
ATGCCAAGGAAAATTACAATAGACTCCATGAAAGGGCGCATATACTTCAGTAACACATGC
CATGACACAAAGTCATGCAGATTTAAGATTCTACAATCTGCTTTAGACGGATCTGATTGC
ATTGAATTATTCAGTCATAATTTACACAACGTTTCAGCTATGGTAGTAGACTCACAATCT
AAAAGATTATACTGGTCTGATCCGGATCGTGAGGTTATAGAATGGTCAAATACCGATGGA
AGCCATCGTACCACGCTTATTGAGAACAGTATAAGTCAACCAGTTGGTTTAGCTGTGTTT
GGTGATTCCATCTATTGGGTGGACTCTCAGGTTCATATTTTAACGAATAAAATCGACGGT
TCAAATCGACGAATTATTCAAAGTCGAGTCCGAAACTTAAAAGCGATCGCTGCAGCCAAG
CTTATCAATCTTGGTGACCGATTACAACACCCATGTTTCACTGATAATGGGGGTTGTTCA
CATATCTGCGTGCCACAAGTTACCGGGGTGACACGGTGTTCGTGCCCCACACATCTTGCT
GTGATAGAAGATTCCAAATGTGGCAAGCCAGTGACGTGTGGTCCAGGTTATTTTCGATGC
AAAACTTTATCGATTTGTATTCCCATGAATTGGAAATGTGACAGTGAGAATGATTGCGAA
GATGCCTCAGATGAAATGAATTGTGAGACAAATAGACTGCCGTGTAAGGATTACGAAGTG
GAATGCAAAGCAGTCTTGCCCCAGTGCGTCAACCAGTCAAAAATTTGCGACGGAACGTAT
GATTGCATCTCGCAAAGTGATGAAATGAATTGCGCGTTTTCTTTAGATTGTGGACCTAAC
CTAAAGGTGTGTCCATCTGGCCAGTGTGTGGCAGTAGGGAGCTCATGTGACTGCACCAAC
TGTCAGCCAATCATTGGCGGCAATGATCAAGACAACTCAATGGTTATAGTGATCGGCATC
GTATGTGGGTGCGTGGTTTTGCTCGGAATCGGTCTTTTTATACGACATTGCATGACCCAC
AACTCTCGTTACCCGCAAGGGGTTGTCATGTTCGCCCCGCACACGAACGGCAACTGCACC
GTCAACGTAGAAATCCAGTCGCGTGCCGACACAACTGAAGTCGTAAACCACCAAAAAACT
AACGGCAACCAGAGCCGTAAAAAGGGGTCAACAAAGGGGAAAGCATCGATTAACCTTTCC
TTTCACCCCAGCGGGAGTAGATCGGGGTCAAATTCCCGGTTTGGGGTCCCATCAAATTGG
CAATTTCCCGTCCATTATACAAAGGATTGCCATTCTATGGATCGTCCCTGTGTTCCAGGG
GCATCAAGGTGTTCAAGCATACAAGCCAAGGTTTTCTCACCGACCACCAACCCCCCACCC
TCCCCTGCAACAGTGAGATCGGGCTCCAAAAGCGGGGACAGGGTTTATTCAACTGATTCT
GGAAGGTCTCACCATAGATGTAAGAATGGATATAAACACAGAAGGTCTCAGCACCGCTAC
CCAATCCATCACCCTCCACCCCCTACCCCATGCAACACAGACACATGCGATGACGTAGAC
CGGGGTTACAGACACGGGGGTTCGAATCGAAGCCCCCCATCAACGAACTCAAGCGTCCCG
CATGAGCCCCCGCCCCCCTACCACCACCATCAGTGTTGTTACCACTGCTACCATCAATAC
CCCCCACAATGTAGACACCCAGATGGCAGCTCGTCAAGCTCGTACCAATGTGAGGACGAC
GATTGCTCCTGTGGTGGTGACTCCCTACCATCTTACCCCCCCTCTTATAATCAGCGGGGG
CGCTCCTGGCGAAGACCTCCACATCGCTCCTACCTCTCATCGGATCTGAATTCGGATTCG
GATCCATTCGCGCCCCCGCCAACCCCACGCAGCCAGTACATGTCGGAATGTTGTTACACC
CACGGTGAAACGACGGAGGCCGACGATCCATTAGACGAAGAAGATGAGACGGTTGATGAT
GATGTCACTAATGACGTCACAGAAAACCTCATTGCAGGATCGGGAGTCACGGAAGATGAG
GAGGGAGGATCTGAAGATGATGCGGACACAGTTTTACTCAATCCGAGGTCATCCCCATCA
GTAACGGAGCGAAGTTTTCGCATCTATAACCCTCCGCCATCCCCAGCCACAGATTCCTCA
TGAAGCAGTGCTGCCAGTTGAAAAACTTAATACAAAAAATAGTGCTCCCAGTTAAAAACC
TCTGCACAAAAGGCAGTGCTGCCAGTTGAAAAACTCGGTACAAAAAACAGTGCTGTCAGT
TGAAAAACTTGTCACAAAAAGCAGTGCTACCAGTTGAAAAACTTGTCATAAAAAGCAGTG
CTCCCAGTTAAAAAACTTGACACAAAAAACAGTACTACCAGTTGAAAAACTTGTCACAAA
AGCAGTGCTCCCAGTTAAATAACTCCTCACAAAAAACAGTGCTACCAGTTAAAAGGTCAG
AAAATGCCAGGCGAATAACTAAAACATGATCGAACAGCACTGCAGAAACATGTATATAAA
TCCAATTCCCTATTGTAATGGGAATGTTTAATGTTTTTACCATTTTTTGTTTTATTTCAT
TTCAAAACCAATAGAACCCTCTGCCAACGCTGTCGTTGCCAACTTTTTTGCATTTTATTC
TTTTTTTTGTTTGTTATCAAATTTTCAGCGGTACACGAAACTTTGCATTTGATCTTGTAT
ATACTGCACTTCAATTCTTCCGAACGAATCATGTTTTTTTTATTGTACAGTATAAACATT
AAGTTTGTCTGTCGTTCTGGTCAACTATCTTGACAAAATAATCGCATAAACGTTTTAGGA
TTTTCAGGTACACTTTTACATTTCTTAGAATTTTAAAGTTTGCAGTGGTAGCCTTTGAGT
TTTTTTACGACGAAAAAAAACACTTTTTTTCGTTTTTTTTACCGCCGTTTTATGCGTGCC
AATTCTATTCTATTTCTATTTTCTGTAGAATAGAATGCGTGCCAATTATTCATATAAGCA
TGAGCCTTTTTAAATTAATTTTTTTGTAAAGTGTACATCAGTCTTCTTACCTCTCTGGTC
ATTGTTCTAGTGCCTGGTTATCATGTCTGAACGATTTGCAATTGCCCAACGAATGTAAAT
AAATTTGGTTTTAACTATT
| Gene3D |
6-blade_b-propeller_TolB-like (IPR011042) - T[24-303] 6.5E-91 - T[345-654] 1.2E-124 - T[655-949] 2.5E-90 - T[955-1313] 5.1E-78 |
| SMART |
LDLR_classB_rpt (IPR000033) - T[48-90] 5.4 - T[93-135] 2.5E-12 - T[136-179] 3.6E-15 - T[180-222] 5.1E-12 - T[235-282] 2.1 - T[377-419] 0.0014 - T[420-462] 3.1E-12 - T[463-506] 3.3E-15 - T[507-549] 1.6E-13 - T[550-590] 2.2E-4 - T[682-724] 8.4 - T[725-767] 1.0E-9 - T[768-811] 4.1E-10 - T[813-855] 1.8E-4 - T[856-897] 9.8 - T[1012-1054] 0.24 - T[1055-1101] 7.3E-7 - T[1163-1205] 4.9E-7 - T[1206-1245] 3.8E-4 |
| ProSiteProfiles |
LDLR_classB_rpt (IPR000033) - T[68-112] 9.831 - T[113-155] 17.326 - T[156-199] 16.909 - T[200-221] 8.044 - T[260-302] 8.833 - T[397-439] 14.147 - T[440-482] 15.888 - T[483-526] 16.143 - T[527-569] 13.358 - T[570-610] 6.42 - T[702-744] 11.688 - T[745-787] 14.704 - T[788-832] 11.711 - T[833-875] 9.019 - T[876-916] 6.42 - T[1032-1078] 10.736 - T[1079-1109] 8.485 - T[1134-1182] 6.606 - T[1183-1225] 15.099 - T[1226-1248] 5.794 |
| Pfam |
LDLR_classB_rpt (IPR000033) - T[113-153] 1.5E-11 - T[156-197] 5.1E-15 - T[440-480] 7.8E-11 - T[484-524] 6.4E-10 - T[529-555] 1.2E-5 - T[745-785] 2.2E-5 - T[788-830] 7.2E-5 - T[1184-1222] 1.3E-5 |
| SMART |
EGF-like_dom (IPR000742) - T[310-349] 17.0 - T[617-654] 0.035 - T[923-962] 0.03 - T[1273-1310] 56.0 |
| SUPERFAMILY |
LDL_receptor-like_sf (IPR036055) - T[1313-1350] 8.25E-10 - T[1356-1394] 2.49E-6 |
| Pfam |
LDrepeatLR_classA_rpt (IPR002172) - T[1314-1350] 8.3E-12 - T[1356-1393] 5.4E-6 |
| SMART |
LDrepeatLR_classA_rpt (IPR002172) - T[1314-1352] 2.4E-14 - T[1356-1395] 2.2E-5 |
| ProSiteProfiles |
LDrepeatLR_classA_rpt (IPR002172) - T[1314-1351] 13.413 - T[1356-1394] 10.963 |
| CDD |
LDrepeatLR_classA_rpt (IPR002172) - T[1315-1350] 2.65598E-11 - T[1357-1393] 5.86151E-5 |
| PRINTS |
LDrepeatLR_classA_rpt (IPR002172) - T[1326-1347] 1.1E-9 - T[1369-1390] 1.1E-9 |
| ProSitePatterns |
LDLR_class-A_CS (IPR023415) - T[1328-1350] . - T[1371-1393] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| LRP4_HUMAN | 35.28 % | 811 | 0 |
| LRP6_HUMAN | 43.337 % | 1333 | 0 |
| LRP5_HUMAN | 43.56 % | 1257 | 0 |