- Transcript 'Phmamm.CG.MTP2014.S5...' >
- Transcript 'KH2012:KH.C2.917.v1....' >
- Transcript 'KH2012:KH.L18.20.v1....'
Transcript Model
Transcript Id
KH2012:KH.L18.20.v1.A.SL6-2
Possible name(s)
ARAF; BRAF; RAF1
Gene model
Location
KhL18 [560,952 / 571,991]
Amino acid sequence
Length: 708
>KH.L18.20.v1.A.SL6-2
EIMAKNDGHNGNDNKRIDKKKLEEDILNLEHVINLTKDSITRLNQEFGGKSHPPSIYLQE
YRELTDRLDDHQKRLENLYDVREQEQSNSNNDTEVQPSYSPQSNQYPHTGTSYGRHVCQS
HDQHFFPTPLAQQTNGQKTHSSRLLSAGGSASSDSPHSPIQQNTTASKPGSEKAIGVIRI
YLPNGKTTVGAIPGKRLKEVLLKSARLKSLRDKLDQCSVYRFGTDDHVDWNSDSGILAGV
QLELRTEDKSFTKSTRILKANHNFARKTFFSLSYCDWCRKILFQGVTCKMCGFKLHQKCI
NEVPDYCITQIQILELEKKIRPQTPSPDSPNTPTDTWPVPGEYNNYPPAHGFPQGVGLAQ
NAAVASLPAPVVVHRDPSHRRSHSPRRDSNEDWEVPEEEIEWGDKIGSGSYGIVYRCRWH
GIVAVKVLNVSNPTPSQLQEFKNEVAVLRKTRHVNILLFMGYTIKNQLCIVTQWCDGSSL
YRHLHMIDTKFDMLQTINIARQTAQGMEYLHAKNIIHRDMKSNNIFLLEDYTVKIGDFGL
ATVKSRWSGSEQLMQPTGSILWMAPEVIRMIDGNPYTFQSDVYAFGVVLYEMTSNTLPYS
HIGNRDMILFQVGRGYLSPDLDLIRSDTPRSCRKLIVDCIKKNREDRPLFPQIWGDLDKI
YKALPRICRSQSDPCSINRAGSSSSEDFFRLILPKSTRTQNSTTLVSP
Nucleotide sequence
Length: 2,949
>KH2012:KH.L18.20.v1.A.SL6-2
CCCGCTCGTATATTTATCAGTTGATTTTAGGGTGAAAATATTCAAATTGGAAACATTATT
ACTATTTGTGTGTGCCTCGTATGAGTCAGTGTTTTGAATACCGTCACCAAAAAAGGTGAC
TGGAAGATCAGTTAGGAGATTATGGCAAAGAATGATGGCCACAATGGCAATGACAACAAA
CGAATTGACAAAAAGAAATTGGAAGAAGATATTTTAAACCTGGAACATGTTATAAACCTC
ACAAAAGATTCCATCACTCGTCTTAACCAAGAGTTTGGTGGAAAGAGTCATCCTCCATCT
ATATACCTCCAGGAATATCGAGAACTGACAGATCGACTTGATGATCATCAAAAACGTCTT
GAAAACCTTTATGATGTAAGGGAGCAGGAACAATCAAATTCAAACAACGATACTGAGGTC
CAACCATCATATTCACCACAGTCGAACCAGTACCCACATACAGGTACCTCCTATGGTCGG
CATGTATGTCAGTCTCATGATCAACATTTCTTTCCTACACCCCTTGCCCAGCAGACCAAT
GGCCAGAAAACCCATTCTTCAAGGCTTCTTAGTGCAGGAGGAAGTGCTTCTTCAGACTCC
CCACACTCACCTATTCAGCAGAACACCACCGCGTCAAAACCTGGATCAGAAAAGGCCATC
GGCGTAATTCGAATCTATCTACCAAATGGAAAAACCACGGTTGGTGCAATTCCTGGCAAA
CGTTTAAAAGAAGTACTTCTAAAATCAGCACGACTGAAAAGCCTTCGGGATAAACTGGAT
CAGTGCAGTGTGTACCGGTTTGGAACTGATGATCACGTGGACTGGAACAGTGATTCGGGA
ATTCTTGCCGGTGTGCAACTCGAACTTCGAACTGAGGACAAGTCTTTTACAAAGTCAACA
CGCATACTAAAGGCAAACCATAACTTTGCGCGAAAAACATTCTTTTCACTCTCCTATTGC
GACTGGTGCAGGAAGATCCTATTTCAGGGCGTCACGTGCAAGATGTGCGGGTTCAAGCTG
CACCAGAAGTGCATCAACGAAGTGCCCGATTACTGCATTACACAAATACAGATACTGGAA
TTAGAGAAGAAAATCCGTCCCCAAACCCCGTCTCCCGACTCGCCCAACACCCCTACAGAC
ACTTGGCCAGTTCCCGGGGAATACAACAATTATCCGCCCGCCCACGGCTTCCCGCAAGGA
GTCGGCTTGGCGCAGAATGCCGCTGTGGCGAGTCTTCCCGCACCAGTTGTCGTGCACAGG
GACCCAAGTCACAGACGAAGTCACTCCCCTCGGCGGGATTCGAACGAAGACTGGGAGGTT
CCTGAAGAAGAAATCGAATGGGGGGATAAGATCGGGTCCGGGTCGTACGGAATCGTGTAC
AGATGTCGTTGGCATGGGATCGTCGCAGTGAAGGTCCTTAATGTATCAAACCCCACACCT
TCTCAACTACAGGAGTTTAAAAACGAAGTCGCAGTTCTAAGGAAAACCCGGCACGTGAAC
ATCCTCCTATTCATGGGTTATACAATTAAGAATCAACTATGTATAGTGACGCAGTGGTGC
GACGGCTCAAGTCTTTATCGCCACCTGCATATGATCGACACTAAGTTCGACATGCTGCAG
ACCATCAACATCGCTCGACAGACCGCACAGGGCATGGAATATCTCCACGCCAAGAACATC
ATACACAGAGACATGAAGTCTAACAATATTTTTCTTCTCGAAGACTACACGGTTAAAATC
GGCGACTTCGGTCTGGCCACTGTCAAGTCAAGGTGGTCAGGTTCGGAGCAACTAATGCAA
CCAACGGGTTCTATTTTATGGATGGCGCCAGAGGTGATCCGTATGATAGATGGGAATCCT
TACACGTTCCAATCAGATGTCTACGCATTTGGCGTCGTGCTGTACGAGATGACGTCTAAC
ACACTCCCATACAGTCACATTGGCAACAGAGACATGATCCTCTTCCAGGTAGGAAGAGGA
TATCTCAGTCCAGATCTTGATCTCATCCGGAGCGACACTCCTCGATCCTGTCGGAAGCTC
ATCGTGGATTGCATCAAGAAGAACAGAGAGGATCGACCTTTGTTTCCTCAGATTTGGGGA
GATCTCGACAAGATTTACAAAGCGCTCCCAAGAATATGCAGAAGTCAGTCCGACCCTTGC
TCCATAAACCGCGCCGGTTCCTCGTCAAGTGAAGACTTTTTTCGATTAATTTTACCGAAG
TCAACAAGGACCCAAAATTCGACTACCCTTGTCAGTCCTTAATTGGACACACGCGGTCGC
TTAACAGATTTCACGGTCGAGTTTAGGTAATTAAATGCATCAAGTGAGCAGTGTGATATG
CATTTGTTTTAGCTCCATTCTTTTTAATATGCCCCTGCGTGTTTGTCAAAATATCAAGGT
ATGCCTCCAGCACAAGCAGCGGTTGCGGGGCCCAACACACGTACATGAATCAAGCGTTAC
CTAGACAGCGCGATTCCGCAGAGGGCGTTTGTAACCTGTTTCATAACCTTTCCAGTTTCG
TGCGAAACTTTGCTTGGCTAACTTGTAATCCCGCTTTTTAACGCTAGGAAAATACGAGGC
GAGCACTGACGGAGATAACTTGTTGGCACTTACTTTTTCCAGCTACGTTTATACTTGATG
TATCGCAATTTAGGTTTCCATTCTATGCTTTGTAGATCATACCTTTGTTCCTTACTGACC
TCGCCTTCTTTGGGCGTGGTGTATCCTCACTAACGGTGATCTTGCTAAACCGAGAAGTAA
GCCAACTGGTCCACGCTTTGCACTAAACAGCCAATACACCATTAAGAATTCTGACCCAGT
TGCTAATTGCGCGAATGTTTCAAAGCAGAAATATAGTAACCGTATATCGTATTTCGTTTT
TCCGCCTGAATTTATTTGCGATGATTTTAATCGAAGATGCAACTATAAAACATACATCAA
GAATTTCTA
| SUPERFAMILY |
Ubiquitin-like_domsf (IPR029071) - T[177-245] 1.5E-10 |
| Pfam |
RBD_dom (IPR003116) - T[178-244] 1.5E-7 |
| ProSiteProfiles |
PE/DAG-bd (IPR002219) - T[261-307] 13.432 |
| ProSitePatterns |
PE/DAG-bd (IPR002219) - T[262-307] . |
| SMART |
PE/DAG-bd (IPR002219) - T[262-307] 3.3E-8 |
| CDD |
PE/DAG-bd (IPR002219) - T[262-307] 2.58532E-11 |
| Pfam |
PE/DAG-bd (IPR002219) - T[262-308] 6.6E-10 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[386-681] 2.97E-74 |
| ProSiteProfiles |
Prot_kinase_dom (IPR000719) - T[400-664] 42.322 |
| SMART |
Prot_kinase_dom (IPR000719) - T[400-661] 5.0E-60 |
| Pfam |
Prot_kinase_dom (IPR000719) - T[403-653] 1.3E-55 |
| ProSitePatterns |
Protein_kinase_ATP_BS (IPR017441) - T[406-426] . |
| ProSitePatterns |
Ser/Thr_kinase_AS (IPR008271) - T[515-527] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| BRAF_HUMAN | 68.317 % | 446 | 5.31E-147 |
| RAF1_HUMAN | 63.259 % | 423 | 2.16E-139 |
| ARAF_HUMAN | 45.596 % | 487 | 9.28E-165 |