- Transcript 'KH2012:KH.C11.698.v1...'
Transcript Model
Transcript Id
KH2012:KH.C11.698.v1.A.SL2-1
Possible name(s)
LGR4; LGR5; LGR6
Gene model
Location
KhC11 [3,230,719 / 3,260,248]
Amino acid sequence
Length: 1,193
>KH.C11.698.v1.A.SL2-1
LMSVLNLLVLCWVVGSSPWVSSRTSGTAGVAMADSQPPQTRKSPPCPQACRCSRNTGFGY
SVDCSSLDLNQVPSSVDELTTFLDLSVNNISVVASKAFSNLHLLQELRLVSDNIETLVPG
AFDSLRALETLMLHNNRITNIPGRSFIDTPNLLDLNLDGNFISELHEDSLEGLQNLESLR
LDDNRLSRVPTEALSKTPNLKALDLALNNIKVIHTGAFRHLTKLRMLNLRENKISRIEDG
AFDGPVKCRILHLEHNQLTEYPRPVTGLTKLRELKLNDNKIQRLPDRAFSKQTNLEILMF
HNNPLKSVGRWTFTNLRNLELLEIVGVEEQEHFPDLSGCNKLRELFVVGGRFTQIPDTLC
GKKSVLQRLIVANNRLQNLGGISNCKMLDGLDISGNALKSLNENEMSNLTFLRTLDLSEN
KISSLAENVFGHSKLVKLNLAYNSFAYLPIRGLSQLRKLNVSGVKNMLYLPPIQFMNHLS
QLEAAYPYHCCQVSNEWVRAHEYEWVGPDDEIIKQSSPAISCHPEPSALTPCDNLLPSVV
VRVVLWLVLVFSSALNMTVVLSSIIRKCRNACRQAHRRQKTPEPVTTTSVTPEQHVMDKF
VQSYDSTGSVSDTFELALCHLAFADFVAGVYIAILVAYDVTTRGNFAEHGAWWQQSLMCR
TAGFFLVMGLQLSFFTVLIATVERYLATMFPLKPEKHISKAVLGLTLSAAWVISIATAIV
TLVSGEEGFPLQERSRRVLPLYNGATCLPWSTHFKYVAVLVGGHVIACLGIVILCVLMYC
ARRKQSWLSAQKHTRRQISLTVACNVTLILPLALIGLLASAVTTYPSAAEPWVFSSESAY
SNQEPAKLNVDLLLTMVMLLISLRFAINPLLYISFSESFRRDMRAAAGWLCCTIRRNRYH
DYDTDDDIDDGFTEPTEFAFHDPNATRQLEASLPVFRHGKIAPDVIQSSGYETHVFGEEF
ANEPFYNMHSDGDLQRKITARRLETTRLVPVMLHAQAYDEDRLSPQLNHHEAKYSQCNSR
DENITISQMSPERIAAEDNKLNYASAQVANKTYIAQGARPKYNTRLPPLIWRKYSPEDAA
NVDGKKLSQSCESSTSKDSGIQSEPDFGVAYSSGCSSLARSSASSHETGDSLDNTDTTYA
RGFLQVVGERTLPRNEAAHTVDAAHLKLNIAANDVRLEKVDLCELPKVGETVL
Nucleotide sequence
Length: 4,623
>KH2012:KH.C11.698.v1.A.SL2-1
GTAGATGTACAGAACTAGAGTGTAAGTTGAAATTTGTTTGAACTGTTGATGCTACAACAC
CGTATGGGTGGGACGATTTAACAAAATCCGAGAGAATATTCACTATCTGTTTGTCACTCC
GAAGTAGTGGAAGTTATATTAACACACAGGAAAAGCGAAATAACTCATGAGCGTCTTAAA
CCTCCTAGTTTTGTGCTGGGTCGTCGGATCTTCGCCGTGGGTCAGTAGCAGGACAAGTGG
TACAGCAGGTGTCGCGATGGCCGACTCACAACCCCCGCAAACCCGCAAATCCCCACCGTG
CCCACAAGCTTGCAGGTGCAGCAGAAATACTGGGTTCGGTTACAGCGTTGATTGCTCGTC
ACTCGATCTTAACCAAGTGCCCAGCTCTGTAGACGAACTAACTACATTTCTAGACTTGAG
CGTAAACAATATATCAGTGGTAGCAAGCAAAGCATTTAGCAATCTACACCTTCTGCAAGA
ATTACGTCTTGTCAGTGACAACATTGAAACTTTGGTGCCAGGAGCATTTGATAGTTTGCG
GGCATTAGAAACTTTGATGCTGCATAACAACAGAATCACGAACATACCCGGCAGAAGCTT
CATAGACACACCGAACCTTTTAGATCTAAATCTCGACGGTAATTTCATCAGCGAACTGCA
CGAGGACTCACTGGAAGGTTTACAAAATCTTGAGAGTCTTCGTTTGGATGACAACCGACT
GTCACGTGTGCCTACTGAAGCGCTCAGTAAAACCCCGAACCTCAAAGCCCTAGACCTTGC
GTTGAACAACATTAAAGTGATACACACCGGAGCGTTCAGACATCTGACCAAGTTAAGAAT
GCTGAATCTACGTGAAAATAAGATCTCAAGAATAGAAGACGGTGCCTTTGACGGTCCGGT
CAAATGTCGCATATTACACTTGGAGCACAACCAACTGACCGAATATCCTCGGCCTGTAAC
CGGCCTCACTAAGCTACGAGAGCTGAAACTTAACGACAACAAGATTCAAAGACTACCAGA
CCGTGCATTCTCAAAACAAACCAACTTAGAGATTTTAATGTTCCACAACAATCCGCTCAA
GTCTGTTGGAAGATGGACCTTCACCAATCTACGCAATCTGGAACTACTAGAAATAGTCGG
TGTCGAAGAACAAGAACATTTTCCTGATCTGTCTGGTTGCAACAAACTAAGAGAACTCTT
TGTGGTCGGGGGACGCTTCACTCAAATACCTGACACACTGTGCGGGAAAAAGTCGGTCCT
GCAGCGCCTCATAGTGGCCAATAATCGCTTACAAAACCTGGGCGGTATCAGCAACTGTAA
AATGTTAGACGGACTTGACATTAGCGGCAATGCATTGAAGTCGTTGAACGAAAATGAAAT
GAGCAATCTAACGTTTCTTCGCACACTGGATTTAAGCGAAAACAAAATCTCCTCTCTAGC
TGAGAACGTGTTCGGGCACAGCAAGCTCGTTAAACTGAACCTAGCGTACAACTCGTTTGC
ATACCTTCCAATACGTGGCCTCTCACAGCTGAGGAAATTAAACGTATCAGGAGTAAAGAA
CATGTTGTACTTGCCACCTATACAGTTCATGAACCATCTGAGCCAACTTGAGGCTGCCTA
CCCTTACCATTGTTGCCAGGTATCGAATGAGTGGGTACGTGCGCACGAGTACGAATGGGT
TGGCCCGGACGATGAAATCATAAAACAGAGTTCACCGGCAATTTCGTGTCACCCCGAACC
CAGCGCTCTTACACCATGCGATAACCTCCTACCGTCGGTAGTGGTTCGTGTGGTATTGTG
GTTGGTCCTTGTGTTTTCCAGCGCCCTTAACATGACTGTGGTTCTTTCTTCCATCATTCG
TAAATGTAGGAACGCATGTCGACAAGCTCATAGGCGGCAAAAGACACCGGAACCCGTTAC
CACCACATCAGTGACGCCCGAGCAACATGTTATGGATAAGTTCGTACAGTCGTACGATTC
CACCGGTAGCGTAAGCGACACCTTTGAGCTTGCTTTGTGTCATTTAGCATTTGCGGATTT
TGTCGCTGGCGTGTATATCGCTATCCTAGTTGCCTATGATGTGACAACAAGGGGTAACTT
TGCGGAACATGGTGCATGGTGGCAGCAATCACTGATGTGCCGCACTGCAGGCTTCTTCCT
GGTTATGGGTCTTCAATTGAGCTTCTTCACAGTGCTTATTGCTACCGTGGAGCGCTACTT
GGCAACGATGTTCCCTCTAAAACCAGAGAAACATATCAGCAAGGCGGTGCTAGGTCTCAC
ACTCAGTGCTGCATGGGTTATATCAATTGCAACTGCTATTGTCACTTTGGTCAGTGGCGA
AGAAGGTTTTCCACTACAAGAGAGGTCACGAAGAGTGCTTCCGTTGTACAACGGTGCAAC
ATGCCTTCCATGGTCCACGCATTTTAAATACGTTGCAGTATTGGTTGGCGGGCACGTTAT
CGCTTGCTTGGGTATTGTCATTCTTTGCGTACTGATGTACTGCGCAAGAAGGAAACAATC
TTGGTTGTCAGCACAAAAGCATACGAGAAGACAGATATCGCTTACTGTCGCTTGTAACGT
GACACTAATTCTCCCACTTGCTCTCATAGGTCTTCTTGCATCGGCAGTAACTACCTATCC
TTCAGCGGCGGAACCTTGGGTTTTCTCCTCTGAGAGCGCTTACTCAAATCAGGAGCCGGC
CAAGTTAAACGTGGATTTGTTACTTACGATGGTCATGCTGCTAATATCCTTACGGTTTGC
CATCAACCCCCTGCTTTACATATCCTTCAGTGAGTCGTTTCGGCGCGACATGAGAGCAGC
TGCCGGTTGGCTCTGCTGTACTATACGTCGAAACCGTTACCATGACTACGATACCGATGA
TGACATTGACGATGGTTTCACAGAGCCAACTGAGTTTGCATTTCACGATCCTAATGCTAC
ACGACAACTAGAAGCTTCTCTTCCAGTGTTCAGACATGGGAAAATTGCACCCGATGTTAT
TCAAAGTAGCGGTTATGAGACCCACGTATTTGGGGAGGAATTTGCCAACGAACCGTTTTA
CAATATGCATTCGGATGGCGATTTACAACGCAAAATAACAGCCCGTCGACTTGAAACAAC
GAGACTCGTTCCAGTGATGTTACACGCACAAGCATATGATGAAGATAGGTTGTCACCTCA
GCTGAATCACCATGAAGCAAAGTATTCTCAGTGTAACAGTCGAGACGAAAATATAACAAT
TTCGCAGATGTCACCGGAGCGCATAGCTGCGGAGGACAATAAGTTGAATTACGCAAGTGC
GCAAGTCGCGAATAAAACTTACATCGCGCAAGGCGCAAGACCGAAATATAACACACGCTT
GCCGCCTTTAATTTGGCGGAAATACTCCCCGGAAGACGCGGCCAATGTAGACGGAAAAAA
GCTCTCGCAGTCGTGTGAGTCCTCAACCTCAAAGGATTCCGGGATTCAGTCGGAGCCAGA
TTTTGGTGTCGCCTATTCAAGCGGGTGCAGTAGTCTTGCACGTTCCAGTGCTTCCAGTCA
CGAAACCGGTGACAGTCTGGACAACACTGATACCACTTACGCGCGTGGTTTTCTTCAGGT
AGTAGGCGAGAGAACATTACCACGCAACGAAGCAGCGCACACGGTTGATGCGGCGCATCT
TAAATTGAATATAGCAGCGAACGATGTCAGGTTAGAGAAAGTTGATTTGTGTGAATTACC
GAAAGTCGGTGAAACCGTTTTATGATGGGATTTTTCTGCGAAACTTGTTTTATTTGCGTG
TGAAACCTTGTTGGCTTTACTGAATGTTTACCTCTACATACTGTTTTTTTTTCGTTTCTG
CAAAGCTTCCCTTTAAACGGCGGTCGCTGTTCTTGCCTACATTTACTTACCTTGTTAATA
TACTTCCAAACATAAAGCCCATATACTGGTAAAAACGTAAAATGAAAAATCATACTCGTC
CTTGTAAAGGTGTTCGCTGAACAACTGTTGTTTGGTTAAATTACTTGGTAACTAGTACAG
TACCTCAGGTGTGGACAGCAAAATTTGGTTTTGTAAATTTTGCACGTTTTGTTTGTTCAT
TCTCTGTATGATGTTCATATATATATATACTGAAGTACAATGGCATGCTCATTTAACTGC
CTTTCCATGTAGCACCCTGGGAGACGGCTACACGTTTTTGCTGGCAATTTTGATTTACCT
CTAATTCCGAATACTCATCTATAACATTCAAATATGGTCAAACAAAATATGTTTTGCAAG
AATGGGATGGCTGTTGTTTAACTACTTCTATTTGCAATAATAAAAACATCACTTTCTACA
ACTGAGTGTGCAGCTTGATTTTTTGTAGATAAATATAAATCTACCATATAAAAAATAGTT
GTTTGGAAGATTGTAGTACTCTCCTTTGTTGTGTATGGGTCATATTAAGCCGATTTCATT
TCCGTACAATAAGGCTTTAAATGCTGCACAGAACATGTGTTTACACACACACCACATCCG
TGATGTCTAGATTTTTCCTGTGAGATATCACTAATACTCAACTGATAAAACAGGCACAAA
CAATGTGGTCACCTAAACACAGATCTTTAATTTGTATTCTTACTTTTACACTTTATGCTG
AAG
| Gene3D |
LRR_dom_sf (IPR032675) - T[44-494] 8.6E-104 |
| SMART |
LRRNT (IPR000372) - T[45-82] 6.0E-4 |
| SMART |
Leu-rich_rpt_typical-subtyp (IPR003591) - T[76-100] 38.0 - T[101-124] 57.0 - T[125-148] 0.0099 - T[149-172] 25.0 - T[173-196] 0.0074 - T[197-220] 6.7 - T[221-244] 5.2E-4 - T[268-291] 8.5E-5 - T[293-315] 45.0 - T[409-432] 1.9E-4 - T[433-456] 310.0 |
| ProSiteProfiles |
Leu-rich_rpt (IPR001611) - T[78-100] 5.517 - T[127-148] 7.781 - T[151-172] 6.765 - T[175-196] 7.25 - T[199-220] 6.618 - T[223-244] 7.412 - T[247-269] 5.001 - T[270-291] 7.589 - T[294-315] 5.664 - T[365-386] 6.511 - T[387-408] 5.748 - T[411-432] 7.466 - T[434-457] 5.163 |
| Pfam |
Leu-rich_rpt (IPR001611) - T[127-186] 2.9E-13 - T[198-258] 9.2E-17 - T[270-325] 3.2E-9 - T[366-422] 9.5E-7 |
| PRINTS |
GPCR_Rhodpsn (IPR000276) - T[540-564] 2.4E-7 - T[666-688] 2.4E-7 - T[702-723] 2.4E-7 - T[854-880] 2.4E-7 |
| ProSiteProfiles |
GPCR_Rhodpsn_7TM (IPR017452) - T[594-872] 18.526 |
| Pfam |
GPCR_Rhodpsn (IPR000276) - T[614-872] 1.8E-11 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| LGR6_HUMAN | 30.826 % | 311 | 4.95E-90 |
| LGR5_HUMAN | 27.574 % | 316 | 6.72E-92 |
| LGR4_HUMAN | 27.715 % | 327 | 1.76E-95 |