- Transcript 'Phmamm.CG.MTP2014.S1...'
Transcript Model
Transcript Id
Phmamm.CG.MTP2014.S145.g04152.01.t
Possible name(s)
CYP3A4; CYP3A5; CYP3A7
Gene model
Location
S145 [186,026 / 200,930]
Amino acid sequence
Length: 1,280
>Phmamm.CG.MTP2014.S145.g04152.01.p
MDKAYGKRLCIRSDADSNQETSHTSAQAITGSSIRNVQNFDLREANIQGASIVGVQGVVN
QNNYYNTPPAKQCPDENSKVAAIEKHQHEHLNGIPESVVPYDKAVKQSNLPVVYPGMHDY
KAYGEEELLMEDKFVSSTQQEVVDLSYEQPVYFDEILNLASTKKFIALIGPPGSGKTTLS
KRLAKLSQPNQSAKFLLRFMDLSYDDRLSYKQLFIDYLCPELDEETKEHSFQWICQNPDK
CVFVFDGYDQATWSLENTKPLNVSYDTPLQIKQLVANLCNKKFFKESLLIFTSRPHTILK
IPSDLRPDVTVHVDDLSTDDMIKLFKAFAGENADELWEILTTKGPQLFSLGHNPLLLQFI
IFAIIHQGLNQVNTITEVFQVVLEHLRYSENARGTDIKQLWKPLGKMAYEGMLRETVVFT
IKNLTDENLDATVVQDVVISFVRNIGFPTQRLFDGDQLFYFSHQMLQEMLAAKYISDYMP
DEEYPKVLEQVAEGGHWSMVRRFLCGFLLKAKNETERSSTLLHLLTKKLENSQGADLLEL
VVDLQECSEEVVDLCAKHVPAKINFAAIPISLSAAHALSQILPKLDQTVERLDLQHCNLK
SDAMKWICEGILKMKHEIKDLVLGGNQMEDDGLEYLTTCMEKMEKLGLAECDITSNGVQV
ISRGLKKLAVPMKTLDLRQNKIGERGVMFLSSDLDKMETLELSDSISSSEEVQILAEGIQ
KRAIPLKKLSLSGHVIGDKGVEYLVICFDKLEVLVLFDCNITSVGVCTICKGLKALKNPM
EELDLSNNEVEDEGISHLTCNFDKMEKLVLASCNITSIGVEKIADGLKKLVIPMKELDLS
NNEVGDEGIGHLTCNFDKMEKLMLGSCSITSIGVQKVADGLKKLVTSMKELELSDNTIED
EGAKHLTDCVDKIKKLILGRCEITDVGKQAIYDALQNYNLPFFKDTLERKKKHGPIFGTY
LGFSVRVAILDPQILKQIQLKESEIFRDRQHTFGRSGGKEMNTALTAAMGDRWKRISVLG
KLSLDVICSSAFNVDMHTQDSNTEESQMLKMGRKLFDIRLGGSIMFMLFSLTRNEIIGNS
ILMILAGFETTGNTMLFVIYNLAVYKDVQEKARQEVEEAVEKHEGLTYDAIMSLKYLTQC
INETLRLYPAIVMNSRYCEKEVTIQGVTIPKDCHIEIHNYAFGRDEEYWENPTLFNPDRM
EDMSKIDPIVFQPFGAGPRNCIGQRFALIEMKMAISKILLNFELDTCPDTPKPPIDITFK
ASVQPKEKIPLKIRRLKSSD
Nucleotide sequence
Length: 3,843
>Phmamm.CG.MTP2014.S145.g04152.01.t
ATGGACAAAGCTTATGGCAAACGTTTGTGCATTAGAAGTGATGCTGATTCTAATCAAGAA
ACTTCACATACAAGTGCACAAGCTATTACAGGGTCAAGTATAAGAAATGTGCAGAATTTT
GATTTGAGAGAAGCGAACATACAAGGTGCATCAATAGTTGGAGTTCAAGGAGTTGTAAAT
CAAAACAACTATTATAACACACCACCTGCAAAACAATGTCCTGATGAAAATAGCAAAGTT
GCTGCCATTGAGAAGCACCAACATGAGCACCTGAATGGAATCCCAGAGAGTGTTGTGCCA
TATGATAAGGCAGTAAAACAAAGTAATCTCCCTGTGGTGTATCCAGGAATGCACGACTAC
AAGGCTTATGGGGAGGAAGAGCTTCTAATGGAAGATAAATTTGTATCTTCCACACAGCAA
GAAGTTGTTGATCTATCATATGAGCAGCCGGTTTACTTTGACGAAATTCTAAACCTAGCC
TCAACAAAAAAGTTTATTGCATTAATTGGTCCACCTGGTTCAGGAAAAACTACGCTTTCC
AAAAGATTGGCAAAGTTAAGTCAACCAAATCAATCTGCTAAGTTTCTTCTTAGGTTCATG
GATCTCAGTTATGATGACCGCCTCTCTTACAAACAGCTTTTTATTGACTATCTTTGTCCC
GAATTGGATGAAGAAACAAAAGAACACTCTTTTCAATGGATATGTCAAAATCCAGATAAG
TGTGTCTTTGTCTTTGACGGCTATGACCAGGCCACCTGGTCACTTGAAAACACAAAACCA
CTCAATGTATCCTATGATACACCTTTACAAATTAAGCAACTAGTAGCTAATCTTTGCAAC
AAAAAGTTTTTTAAAGAGTCTTTGTTGATATTTACGTCTCGTCCCCACACGATACTTAAA
ATTCCCTCAGATCTTCGCCCAGATGTCACAGTTCATGTTGATGATCTTTCAACTGATGAC
ATGATAAAGCTGTTTAAAGCATTTGCAGGAGAAAATGCAGATGAATTGTGGGAAATTTTA
ACCACCAAGGGACCACAGTTGTTTAGTCTTGGCCACAACCCTTTGCTGCTACAATTCATC
ATTTTTGCCATTATACACCAGGGATTAAACCAAGTAAACACCATTACTGAGGTTTTCCAA
GTTGTTTTAGAGCACCTCAGATACTCTGAAAATGCTCGTGGCACAGATATTAAACAACTG
TGGAAACCACTTGGTAAAATGGCATATGAAGGCATGCTGCGGGAAACGGTTGTTTTTACC
ATAAAAAATCTTACAGATGAAAATCTTGATGCCACTGTTGTCCAAGATGTAGTCATATCC
TTTGTTCGTAACATTGGGTTTCCAACACAACGCCTGTTTGACGGTGACCAGCTCTTTTAC
TTCTCACATCAAATGTTACAAGAGATGTTGGCAGCCAAGTACATTAGTGATTACATGCCA
GATGAAGAATATCCCAAAGTCCTAGAACAGGTAGCTGAAGGAGGCCATTGGTCGATGGTT
CGTCGATTTCTGTGTGGATTTTTACTAAAGGCCAAAAATGAAACAGAGAGATCTTCAACT
CTTCTTCATTTGCTGACAAAGAAGCTGGAAAACTCGCAGGGAGCAGATTTGCTTGAACTG
GTGGTTGATTTACAAGAATGTAGTGAAGAAGTGGTGGATTTATGTGCAAAGCATGTCCCT
GCCAAAATTAATTTTGCTGCTATTCCAATTTCATTAAGTGCAGCTCATGCCTTGTCTCAG
ATACTTCCAAAGTTGGATCAAACTGTTGAAAGGTTGGATCTACAGCACTGCAATCTAAAA
TCTGATGCTATGAAGTGGATTTGTGAGGGAATACTTAAAATGAAACATGAGATAAAAGAT
CTTGTTTTGGGTGGAAATCAGATGGAGGATGATGGTTTAGAGTATCTAACAACTTGCATG
GAAAAAATGGAGAAATTGGGCCTGGCAGAATGTGATATTACTTCCAATGGCGTTCAAGTG
ATAAGCAGAGGACTAAAAAAGCTTGCTGTTCCAATGAAGACACTTGACTTGCGTCAAAAC
AAGATAGGAGAAAGGGGTGTCATGTTTCTATCGAGTGACTTAGACAAAATGGAAACATTG
GAACTAAGTGATTCAATCAGTTCCAGTGAAGAAGTTCAGATTTTGGCTGAAGGAATTCAA
AAGCGTGCCATTCCTTTAAAAAAGCTTAGCCTTAGTGGTCATGTAATAGGGGACAAGGGT
GTGGAGTATCTTGTCATTTGCTTTGACAAGCTTGAAGTGTTGGTGCTGTTTGATTGCAAT
ATCACATCTGTTGGAGTTTGTACAATATGTAAAGGACTCAAAGCACTCAAAAATCCAATG
GAAGAGCTTGATTTAAGTAACAATGAAGTGGAAGATGAAGGCATCAGTCATCTAACATGC
AACTTTGATAAAATGGAGAAGTTGGTGCTGGCGAGCTGCAACATTACCTCAATAGGAGTT
GAAAAAATTGCTGATGGACTCAAAAAACTTGTTATTCCTATGAAAGAGCTTGATTTAAGT
AACAATGAAGTGGGTGATGAAGGCATTGGTCATCTAACATGCAACTTTGATAAAATGGAA
AAGTTGATGCTAGGGAGCTGCAGCATTACCTCAATAGGAGTTCAAAAAGTTGCTGATGGA
TTGAAAAAGCTTGTCACTTCTATGAAAGAGCTTGAACTGAGTGATAACACCATAGAGGAT
GAGGGTGCAAAACACTTAACAGATTGTGTGGACAAGATTAAGAAGCTCATTCTAGGCCGC
TGTGAAATCACTGATGTTGGAAAGCAGGCAATATATGATGCACTTCAAAATTATAACCTA
CCTTTTTTTAAGGACACTCTTGAAAGAAAGAAAAAACATGGTCCAATATTTGGGACTTAT
TTGGGATTTAGTGTGCGGGTTGCTATCCTTGACCCCCAAATCCTAAAACAAATTCAACTG
AAGGAAAGTGAAATCTTTCGAGATCGACAGCATACGTTTGGTCGAAGCGGTGGAAAAGAA
ATGAACACAGCTCTAACAGCAGCAATGGGTGACCGATGGAAACGAATCAGTGTTCTTGGA
AAACTCTCTCTGGATGTTATTTGTTCCTCAGCTTTCAATGTTGATATGCATACACAGGAT
TCCAATACAGAAGAATCGCAAATGTTAAAAATGGGGCGAAAACTTTTTGACATTAGATTA
GGAGGATCAATTATGTTTATGTTATTCAGCCTGACAAGAAACGAAATAATTGGAAACAGT
ATACTGATGATTTTAGCTGGATTTGAGACCACTGGAAATACAATGTTGTTTGTGATTTAC
AATCTTGCAGTTTACAAAGATGTACAGGAAAAGGCACGCCAAGAAGTCGAAGAAGCTGTT
GAAAAACATGAAGGACTAACATACGATGCAATTATGAGCTTAAAATACTTGACTCAATGC
ATCAATGAGACACTGAGATTGTACCCAGCAATTGTTATGAACTCTCGCTACTGTGAAAAA
GAGGTGACAATACAAGGAGTCACAATTCCAAAGGATTGCCACATAGAAATCCACAACTAT
GCATTTGGGAGAGATGAGGAGTACTGGGAAAATCCAACACTGTTTAATCCTGACAGAATG
GAGGACATGAGTAAAATTGACCCTATAGTGTTTCAACCATTTGGAGCCGGTCCACGAAAC
TGTATTGGACAGAGATTTGCGCTCATTGAGATGAAAATGGCAATTTCCAAGATTCTGCTC
AACTTTGAACTTGATACTTGTCCAGATACACCAAAACCACCCATTGATATCACCTTCAAA
GCAAGTGTTCAGCCCAAAGAGAAGATCCCACTTAAAATCAGACGTCTAAAATCTTCAGAT
TAA
| SUPERFAMILY |
P-loop_NTPase (IPR027417) - T[153-360] 3.75E-15 |
| SMART |
AAA+_ATPase (IPR003593) - T[162-385] 0.0024 |
| ProSiteProfiles |
NACHT_NTPase (IPR007111) - T[164-295] 12.629 |
| Pfam |
NACHT_NTPase (IPR007111) - T[166-326] 3.1E-19 |
| Gene3D |
LRR_dom_sf (IPR032675) - T[520-751] 2.7E-29 - T[752-939] 5.9E-36 |
| SMART |
Leu-rich_rpt_Cys-con_subtyp (IPR006553) - T[640-664] 130.0 - T[723-747] 89.0 - T[748-772] 330.0 - T[777-801] 600.0 - T[802-826] 160.0 - T[856-880] 76.0 |
| Pfam |
Leu-rich_rpt (IPR001611) - T[672-690] 1.6 - T[726-744] 0.1 - T[780-798] 0.065 - T[834-849] 0.037 - T[886-906] 0.0018 |
| SUPERFAMILY |
Cyt_P450_sf (IPR036396) - T[940-1274] 9.3E-79 |
| Gene3D |
Cyt_P450_sf (IPR036396) - T[940-1069] 4.7E-6 - T[1070-1279] 2.2E-74 |
| PRINTS |
Cyt_P450_E_grp-I (IPR002401) - T[961-987] 8.8E-11 - T[1178-1202] 8.8E-11 - T[1211-1221] 8.8E-11 - T[1221-1244] 8.8E-11 |
| Pfam |
Cyt_P450 (IPR001128) - T[1070-1269] 8.2E-64 |
| PRINTS |
Cyt_P450 (IPR001128) - T[1086-1103] 7.4E-12 - T[1139-1150] 7.4E-12 - T[1212-1221] 7.4E-12 - T[1221-1232] 7.4E-12 |
| ProSitePatterns |
Cyt_P450_CS (IPR017972) - T[1214-1223] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| CP3A4_HUMAN | 39.806 % | 179 | 7.77E-48 |
| CP3A7_HUMAN | 41.935 % | 172 | 8.64E-46 |
| CP3A5_HUMAN | 40.488 % | 176 | 5.88E-47 |