- Transcript 'KH2012:KH.C3.199.v1....' >
- Transcript 'Phmamm.CG.MTP2014.S5...'
Transcript Model
Transcript Id
Phmamm.CG.MTP2014.S522.g09727.01.t
Possible name(s)
ALK; LTK; ROS1
Gene model
Location
S522 [38,518 / 54,206]
Amino acid sequence
Length: 693
>Phmamm.CG.MTP2014.S522.g09727.01.p
MPKVYSIAGNENGIHWLNSSQQNLYTLTNNSGETVTQTLLSEVASSDQDAACNLFSNSLP
PPSVTETTGSSILLNISSVQTTATSFPPACSPYDIVNTSQVHFSVLYQNTNSVSCLSSPS
CMESRIEDVENPVLNNLRPNTSYEIQIAVYRTLHNSTAVSISQQLLVNTTCGISLEPANL
QCLPQSFNEVYIVWEPPVILNTEEVRYQVAVQTGLHDIPTGTLQFTKFTQQTLLYQVRAF
PVDCPALEGSYSSSNITCAPFDAPKQLTIVDVTSHTITVTWEPYPPGQIRQIVVLWSLRS
ERDKWTESLPLEGSATRETITDLIADTGYLLRSKITYVTGRVAESNQQVEADTLRGRPNS
PTNVTIKGETPDGVICWNTPISQDDSSDIIEYVIEARQVYAVNGAGRGDTSAVTSPYQFT
LPIDNSRYKWIVIGSSVGTTFFVLIIILAFVSQIRHMTSLAMAAASNGGRINLPDNYMKN
LPLFPRDKLALDTLLGSGAFGEVYKGIAIDIRGGEAGIEYPVAVKTLKDGASDSEKCEFL
MEAYFMSLFDHPNIISLLGVCLDNEPQFLILELMEGGDLLKYLRQARQTQMLSAKLHMMD
LLDICLDLAAGCQYLETQHFIHRVVKIGDFGLARDIYRNDYYHKEGEGLLPVRWMAPENL
TLKIYTVQSDVWITPNLDKGLLRYKFGVWSNDT
Nucleotide sequence
Length: 2,082
>Phmamm.CG.MTP2014.S522.g09727.01.t
ATGCCAAAAGTTTACAGCATTGCGGGGAATGAAAATGGAATCCATTGGTTGAACAGTAGT
CAACAGAATCTATACACTCTCACCAATAACAGTGGAGAAACTGTGACACAAACTTTACTG
TCAGAAGTAGCATCTAGCGACCAAGACGCAGCCTGCAACTTATTCTCCAACTCTTTGCCT
CCACCAAGTGTTACTGAGACGACCGGAAGTAGTATTTTGCTTAATATCTCATCCGTTCAA
ACTACAGCTACCTCTTTTCCCCCTGCTTGCTCACCCTATGATATTGTTAACACATCACAA
GTGCACTTCTCTGTTTTGTATCAAAACACAAACTCAGTTAGCTGTTTGTCAAGTCCAAGC
TGCATGGAAAGTAGAATTGAAGACGTCGAAAACCCAGTTTTGAACAATCTTCGTCCCAAC
ACAAGTTACGAAATACAAATTGCTGTTTATCGAACATTACATAACTCAACAGCTGTCTCC
ATTTCACAACAACTACTTGTCAACACAACTTGTGGAATTTCATTAGAACCAGCAAATCTC
CAATGCTTGCCACAATCATTCAATGAGGTTTATATTGTATGGGAACCACCAGTCATTCTT
AACACAGAAGAAGTAAGATATCAGGTTGCTGTTCAAACTGGATTACATGACATCCCAACA
GGCACCCTTCAGTTCACGAAATTCACACAACAAACACTCCTTTATCAGGTTAGGGCATTT
CCCGTCGACTGTCCGGCGCTTGAGGGCTCATACAGCTCATCCAACATAACTTGCGCTCCG
TTCGACGCCCCAAAACAATTGACGATTGTTGACGTCACAAGCCACACAATCACGGTCACG
TGGGAGCCGTACCCGCCGGGACAGATTCGTCAAATCGTTGTCTTGTGGTCCCTGCGATCA
GAACGAGACAAGTGGACCGAAAGTCTACCATTAGAGGGCAGTGCTACACGAGAGACGATC
ACTGATTTGATTGCTGACACTGGTTACTTGTTGAGATCTAAAATTACTTACGTCACGGGA
AGAGTAGCAGAGTCCAATCAACAGGTGGAGGCAGACACGTTGAGGGGAAGACCCAACTCC
CCAACCAACGTTACAATCAAGGGTGAAACACCTGATGGGGTAATCTGCTGGAACACACCC
ATTTCACAAGACGACTCCTCGGATATTATCGAATACGTTATTGAGGCTAGGCAAGTGTAC
GCAGTGAACGGCGCCGGACGAGGGGACACCAGCGCCGTTACGTCACCGTACCAGTTTACA
CTCCCGATCGACAATAGCAGATACAAATGGATTGTAATAGGATCATCTGTAGGAACAACT
TTCTTTGTTTTAATCATCATTCTCGCATTCGTATCACAGATACGGCATATGACAAGTCTT
GCAATGGCGGCGGCCAGCAACGGTGGAAGGATAAACTTGCCTGACAACTACATGAAGAAC
CTCCCTCTATTTCCACGGGATAAACTTGCACTTGATACTTTACTAGGAAGTGGAGCTTTT
GGCGAAGTGTACAAAGGAATAGCGATTGACATAAGAGGTGGAGAAGCTGGAATCGAATAC
CCAGTAGCAGTAAAAACTTTGAAAGATGGGGCAAGTGACAGTGAAAAGTGCGAGTTTCTC
ATGGAAGCTTACTTTATGAGTTTATTTGATCATCCCAACATCATTTCACTTCTGGGAGTC
TGTCTTGATAACGAGCCTCAGTTTCTGATCCTTGAACTTATGGAGGGAGGTGACTTACTA
AAGTATCTGCGGCAAGCTCGCCAAACTCAAATGCTTTCGGCTAAACTTCACATGATGGAT
TTACTCGATATTTGTCTCGATCTTGCCGCTGGGTGTCAGTATTTGGAGACGCAACATTTT
ATTCACAGGGTGGTAAAAATCGGGGATTTTGGACTCGCGAGAGACATCTACCGGAACGAT
TATTACCACAAGGAAGGAGAGGGCTTGTTGCCTGTACGCTGGATGGCGCCAGAGAACCTT
ACACTAAAGATTTACACAGTTCAGAGCGACGTATGGATTACACCTAACCTAGATAAAGGC
CTCTTACGGTACAAGTTTGGTGTTTGGTCAAATGACACGTAA
| SMART |
FN3_dom (IPR003961) - T[56-156] 8.5 - T[174-249] 76.0 - T[261-342] 0.28 - T[358-440] 29.0 |
| SUPERFAMILY |
FN3_sf (IPR036116) - T[92-228] 8.93E-10 - T[262-416] 1.27E-12 |
| ProSiteProfiles |
FN3_dom (IPR003961) - T[176-262] 6.912 - T[263-356] 15.337 |
| Gene3D |
Ig-like_fold (IPR013783) - T[257-353] 9.7E-11 |
| CDD |
FN3_dom (IPR003961) - T[262-332] 3.24772E-8 |
| Pfam |
FN3_dom (IPR003961) - T[262-332] 3.4E-6 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[473-672] 1.85E-46 |
| ProSiteProfiles |
Prot_kinase_dom (IPR000719) - T[489-693] 21.842 |
| Pfam |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[490-672] 4.9E-50 |
| ProSitePatterns |
Protein_kinase_ATP_BS (IPR017441) - T[495-525] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ROS1_HUMAN | 31.266 % | 261 | 4.14E-74 |
| ALK_HUMAN | 44.076 % | 182 | 7.43E-48 |
| LTK_HUMAN | 43.814 % | 168 | 1.2E-43 |