- Transcript 'KH2012:KH.C5.411.v1....' >
- Clone 'citb035a05' >
- Transcript 'Phmamm.CG.MTP2014.S7...'
Transcript Model
Transcript Id
Phmamm.CG.MTP2014.S735.g11585.01.t
Possible name(s)
NOTCH1; NOTCH2; NOTCH3
Gene model
Location
S735 [35,176 / 50,534]
Amino acid sequence
Length: 1,605
>Phmamm.CG.MTP2014.S735.g11585.01.p
TGPCMNGGTCIDDVNTYKCLCVRGFTGAACDQDIDECASTPCANGATCQDFVNSYTCTCQ
AGFIGDDCSINVNECDYGTCVNGGSCVDGINSYTCSCLAGYTGTYCDVDIDECLSAPCRN
GATCSHVINGFQCHCPYGYQGNTCAELIDRCSPNPCHNRASCTQSGTSFSCLCPPGYTGV
YCDIPSVSCAVAEADAPSGELCQHAGTCVDSGVTHYCSCAPGYTGSYCETNIDECESQPC
LNGGTCTDYISTYSCTCLQGFQGSNCQVNVNECSSNPCNNGGTCIDLVNSYTCNCVVGST
GDRCEVDLDDCANSPCQNGGSCLDQLGGFVCECLPGFTGTSCEGDVNECLSNPCDAEGTA
SCVQGENSYRCDCNEGYTGDSCDQKLSSCANLPCRNGATCTDNPIEPTGYRCHCRPGYRG
KNCEQTMSMCSGGLVCYNGGTCADQTCFCPENYGGRKCIYKVPGYPAGPGSDDLDIPQVI
EKVCQDPFCATLRGNNKCDQQCNTWECEYDGGDCSLGVRDPWETCTAALQCQLLFRNGMC
DQQCNNEECLYDGYDCEEPQDACPSHYQEYCNENYGNGHCDVGCNTYGCGYDGLDCEKNY
PEQKAEGILVVTVMITPEDFMKVKSDFLRILGVVLHCIVELQVDQQGQPMIEPIYAELAR
KKRSVWELFGWEKSSTVIFFNETVHERMRRAAAGTVTGSKLYLLLNNQKCIQEEDSCFDD
TQEAASYFGARAASSTLRTGYDIERIESTTGPEGEQPTNYSYIIGAAAGFLVVLVIIGVL
THHKRKRVSSKLWPPEGFHPSSKKMRKEPIGQDDLHLKDLNDGIHSTELTQLDSAPFINK
WDHQQHNKAHRYLPDQAESVEFLPNGSNSGYHPNGHKPSSRDDVTDTRKWTPQHMEAADV
PRNCSAGPITELTPPPQVDMNSDVNARGPDGVTPLMLASTRGSGVETGLSDEESGDSAGD
GNEGSDSMIASLLLQGASLSAQTDRTGETALHLAARYARADAAKRLLDAGADANMKDLTG
RTPLHSAVAADAQGVFQILLRNRATDLDARTNDGTTPMILAARLAVEGMVEELINAHADV
NAVDDHGKSALHWAAAVNNVQVVAILLRAGCNRDAQTEREETPLYLGAREGSYETVRILL
DHYANRDITDHMDRLPRDIAQERLHTDIVQLLDEYNLVRSPQLPPGHMPSHMTGLMRDSY
MPHLKNQGKKTRRQAGRGDGKTGRKSKKAAASQRPPSSGATVDSISPNSDGTPPNMGLMH
PNGMGYNGESTLSPGTASLSSPATTYSTGGGGVHPHMPPQQQQQHHHHHHLRHPIAPQFS
NGSMPNVDERLLPYQRSLPTPPRLSHPPHGGAMFHPRHHNQMQTSHTGLELNMGQIPAGQ
IPQEWMRNEMMMQQHHQMHQPGGLSQIASYRALGITDQQGLQHIRGDAVSADQRRYADLV
GSKVHQQQQQQQQHHLQQQQQQMQQMHMNQQQRLNGFMQQQPSPPVQTNVSMPQVMSNLV
EKYPTPPSIHNHILSPGSDNLSPSAIQPGINKHLQQDISYETPSPDSPDQWSSSSPRSNS
DWSEGIRSPTDPMPGNHHHPHPTHQQQLRVFPPQNPAGPGKMQAA
Nucleotide sequence
Length: 5,922
>Phmamm.CG.MTP2014.S735.g11585.01.t
CACAGGTCCATGCATGAACGGCGGCACTTGCATTGATGACGTCAACACGTACAAATGCTT
GTGCGTACGTGGCTTCACTGGAGCAGCATGTGACCAAGATATTGACGAATGCGCCTCAAC
ACCTTGTGCTAATGGCGCAACTTGCCAAGATTTTGTAAACAGCTATACATGTACTTGCCA
GGCTGGATTTATCGGCGACGATTGCAGTATAAACGTGAACGAATGTGATTATGGAACGTG
TGTAAACGGTGGAAGCTGTGTGGATGGAATCAACTCTTACACGTGCTCATGCTTGGCGGG
TTACACAGGGACTTATTGCGACGTCGACATTGACGAGTGTCTCTCTGCACCTTGTCGGAA
CGGAGCCACATGCAGTCACGTGATCAACGGCTTCCAATGCCATTGTCCTTACGGTTACCA
GGGAAACACATGCGCTGAGCTTATTGACCGCTGCTCTCCCAATCCCTGTCACAACCGAGC
AAGCTGTACACAATCTGGTACATCATTCTCCTGTCTCTGTCCTCCTGGTTACACTGGTGT
TTATTGTGATATTCCAAGTGTGTCTTGCGCCGTTGCAGAAGCTGATGCTCCGTCTGGTGA
ATTGTGCCAACATGCTGGTACATGTGTAGACAGTGGTGTGACCCATTACTGTTCGTGTGC
ACCAGGATATACTGGAAGTTATTGTGAAACCAATATTGACGAATGTGAATCCCAACCATG
TCTAAATGGCGGCACATGCACCGATTACATTTCAACATATTCTTGCACTTGTCTTCAAGG
ATTTCAAGGTTCAAATTGTCAGGTTAACGTGAACGAATGTTCGTCCAATCCTTGTAATAA
CGGTGGCACGTGCATTGATCTGGTGAACAGTTACACATGTAACTGTGTGGTAGGAAGCAC
TGGCGACAGATGTGAAGTCGACTTGGACGATTGCGCCAATTCGCCTTGTCAGAACGGAGG
GAGCTGCTTGGACCAACTCGGTGGTTTCGTCTGCGAATGTTTGCCCGGTTTTACTGGCAC
TAGTTGCGAGGGTGACGTCAACGAGTGCTTGTCGAACCCGTGTGATGCTGAAGGCACTGC
AAGCTGCGTTCAGGGCGAGAACAGTTATAGATGCGATTGTAATGAGGGTTACACCGGCGA
CTCGTGCGACCAGAAACTATCGAGCTGTGCCAACCTGCCATGTCGCAACGGAGCCACCTG
CACTGACAATCCGATTGAACCGACCGGCTACCGATGCCACTGCCGACCGGGATACAGAGG
AAAGAACTGCGAGCAGACCATGTCTATGTGTAGCGGCGGGTTGGTTTGTTACAATGGAGG
GACTTGTGCGGATCAGACTTGCTTCTGCCCTGAGAATTACGGCGGAAGGAAATGTATTTA
CAAAGTTCCAGGTTACCCTGCTGGTCCCGGAAGCGACGATCTTGATATTCCACAAGTCAT
CGAAAAAGTTTGTCAGGACCCCTTTTGCGCCACCTTGCGAGGGAACAACAAGTGTGACCA
ACAATGCAACACTTGGGAATGCGAATACGACGGCGGCGATTGTTCGTTGGGGGTGCGCGA
TCCATGGGAAACATGTACTGCTGCTCTGCAATGCCAATTGTTGTTCCGCAATGGTATGTG
TGATCAACAGTGCAATAATGAGGAATGCTTATATGATGGTTATGACTGTGAGGAGCCTCA
AGATGCTTGCCCATCTCACTATCAGGAATATTGCAATGAGAATTACGGCAATGGACATTG
TGATGTCGGTTGTAACACGTATGGATGTGGATATGATGGTTTGGATTGTGAAAAAAATTA
CCCTGAACAAAAAGCAGAGGGAATTTTGGTCGTCACGGTAATGATCACACCTGAAGATTT
CATGAAAGTAAAGAGCGACTTCCTTCGTATTCTCGGTGTTGTGTTGCATTGTATTGTTGA
GCTGCAAGTCGACCAGCAAGGCCAACCCATGATTGAACCAATTTATGCTGAGCTTGCACG
TAAGAAAAGATCAGTGTGGGAATTATTCGGCTGGGAAAAATCTTCAACCGTCATCTTCTT
CAATGAAACTGTCCATGAACGAATGCGTCGTGCTGCTGCCGGCACCGTCACTGGTTCAAA
GCTCTATCTCTTGCTGAACAACCAGAAATGCATTCAAGAGGAAGACTCCTGTTTCGACGA
CACCCAAGAAGCTGCTTCATACTTCGGAGCACGTGCAGCATCTTCAACATTGCGAACTGG
TTATGACATTGAAAGAATTGAATCCACCACTGGACCCGAAGGCGAACAACCTACCAATTA
CTCCTACATTATTGGGGCAGCAGCTGGATTTCTTGTTGTGCTGGTTATAATTGGCGTCCT
AACTCACCACAAGAGGAAGAGGGTTTCCAGTAAACTTTGGCCTCCAGAAGGATTCCATCC
TAGCTCAAAGAAAATGCGCAAAGAACCGATTGGACAGGACGACTTGCATCTTAAGGATCT
CAACGATGGAATACATTCAACCGAACTAACCCAGCTCGATTCAGCTCCGTTTATCAACAA
ATGGGATCATCAACAGCATAACAAGGCACACAGATATCTTCCAGACCAAGCTGAATCTGT
AGAGTTCCTTCCCAACGGAAGTAATTCCGGTTACCACCCAAATGGACATAAACCCTCAAG
TCGCGATGACGTCACTGACACACGTAAATGGACCCCACAACATATGGAAGCTGCTGATGT
ACCCAGGAACTGCTCGGCTGGACCAATAACCGAACTCACCCCGCCGCCCCAAGTCGACAT
GAACAGTGATGTTAACGCTAGGGGACCTGACGGTGTAACGCCCCTTATGTTGGCTTCCAC
GAGGGGTAGCGGAGTAGAAACCGGTTTAAGCGACGAAGAATCGGGTGACAGTGCTGGTGA
TGGCAATGAAGGAAGTGATAGCATGATTGCAAGCTTGCTGCTTCAAGGAGCTTCGTTGAG
CGCACAAACTGACAGAACCGGTGAAACTGCACTGCACTTGGCTGCAAGATATGCCCGTGC
TGATGCCGCAAAACGTTTGTTGGATGCTGGAGCAGACGCCAACATGAAGGACTTGACGGG
TCGAACACCCCTACACTCTGCAGTGGCAGCCGATGCCCAAGGAGTTTTCCAAATTCTGCT
CCGAAATCGCGCAACCGATCTCGATGCAAGAACCAACGACGGAACGACACCAATGATTTT
GGCTGCCCGACTCGCTGTGGAAGGAATGGTTGAAGAACTTATCAACGCTCATGCGGATGT
CAACGCTGTGGACGATCACGGCAAGTCGGCGCTTCACTGGGCAGCAGCTGTGAACAATGT
ACAAGTGGTCGCCATATTGCTACGTGCCGGGTGCAACAGAGACGCACAGACTGAACGCGA
GGAGACTCCACTGTATCTGGGAGCCAGAGAGGGAAGCTACGAAACTGTGAGAATCCTGCT
CGACCATTACGCCAACAGGGACATTACTGACCACATGGACAGGCTTCCGCGGGACATAGC
TCAAGAGCGCCTCCACACGGATATTGTGCAGCTTCTTGATGAATATAATCTCGTGAGAAG
CCCACAACTTCCACCTGGGCACATGCCTTCACACATGACTGGCCTTATGAGGGACTCATA
CATGCCACATCTCAAAAATCAAGGCAAAAAAACACGACGTCAAGCGGGTCGAGGTGACGG
AAAAACTGGTCGCAAATCGAAGAAAGCAGCCGCTTCACAGCGTCCTCCGTCGTCAGGGGC
CACCGTGGACAGCATTTCACCCAACAGCGACGGCACCCCACCCAACATGGGGCTCATGCA
CCCCAACGGAATGGGTTACAACGGGGAAAGCACCCTGTCCCCAGGAACGGCCTCCTTATC
ATCACCAGCCACTACGTACAGCACTGGGGGGGGGGGTGTGCACCCCCACATGCCCCCCCA
ACAGCAGCAGCAACACCACCACCATCACCACCTCCGCCACCCGATTGCCCCGCAGTTCAG
CAACGGCTCAATGCCGAACGTGGATGAGCGTCTCCTTCCGTACCAGAGGTCACTTCCAAC
TCCCCCCAGGCTCTCACATCCGCCACACGGGGGCGCTATGTTCCACCCACGTCATCACAA
CCAGATGCAAACCAGCCATACTGGTTTGGAACTGAACATGGGCCAGATTCCAGCAGGACA
GATTCCCCAGGAGTGGATGAGAAACGAAATGATGATGCAGCAACACCACCAGATGCACCA
GCCGGGTGGACTTTCTCAAATTGCTTCGTATCGGGCGCTTGGAATCACAGACCAGCAGGG
TCTTCAACATATCCGAGGCGATGCAGTCTCCGCTGACCAAAGAAGATATGCCGATCTTGT
TGGGTCTAAAGTCCACCAACAGCAACAGCAGCAACAACAGCATCACCTTCAACAGCAACA
ACAGCAGATGCAACAAATGCATATGAATCAACAGCAAAGGCTCAACGGATTTATGCAACA
ACAACCCTCTCCACCTGTGCAGACAAATGTGTCAATGCCCCAAGTTATGTCAAACCTTGT
GGAGAAATACCCAACTCCACCATCAATCCACAACCACATTTTATCACCTGGCTCCGACAA
TCTATCTCCTTCTGCCATTCAACCAGGGATCAATAAACACTTGCAGCAGGATATTTCATA
CGAGACCCCAAGTCCAGACTCACCTGACCAATGGTCGAGTTCCTCACCCCGAAGCAACTC
CGACTGGTCTGAGGGTATTCGAAGCCCCACTGACCCCATGCCGGGGAACCACCATCACCC
CCACCCGACCCACCAACAGCAACTTAGGGTATTCCCCCCACAGAATCCCGCCGGGCCAGG
TAAAATGCAGGCAGCTTGATTGGACCAAAGGTGTTTTTGATTTTCTGCCTGTTCATTCCA
CCGCTGGGGGTCGCCGCGCGTGCCTTGATGACGTCATCCAGAGTGGGACCAAAGAATTTT
TACTGCGTTTTTATACGAGTTTTAGTTGAGGGCCAAAACACGGCTTTTTTCGTTTATTTC
CAAAATTTTGACCTATTGTTACACATAAAACTTCCTTTCTTAAACACCGCTCCATTGTGA
TGTCACAGAAGTTTTGGACCGTGGTTTTACACAGTGTGTCTAGGTGGGCGCCCCTATATT
TTTGTTCAAGTTAATTTCTCGTTTGTTGACTTAACCATCTCGTTTTATTGCCCGATTATT
TTCTATGTGTGTTATTTATGTTGGGCGACCATGCTACATCCAACGGGCCAGTATTATACC
TATTGTCGCGATCGCTATTCGTTAAGGATTCCATGACGTTGTTTGTGGGGATTCCCGGTA
TTTTATTACGTCATGTGAATTAATTACGTCACGATGGAAGCGTTTTGTATTTTTTTGAGA
TTTGAATTTTCTCCGTTTTGTTGCGTTGCGTCTTTTTTAAATGCCACTCTTTCCTTTTTC
TTCAAGCTCCTAGTTTTTCGTCTATTGCGTCACTGAAGCGCAGATCAAAGGCACAACAAA
TACCGAACAGATAGACGGACACGAGTTGCCCCCTTTTCTCGTTTTTTTTTGATAATTTTA
ATAACGAACATTGTCGTTTTGAAGCGATTTTCTACTTTTTATACGACTCTGTTTTACAAT
TTCAATCCAGCGTCTAATACACGTTTTTATTATTTCAAGTTTAAAACCTAAATCTATCCT
TAAATTTATAAGTACTTAAAGGCGTCAAGAACATTTAAAAGAGTTACGAACAGATTTAAA
GCAATCCATTTTTCTCACATTTTCGTTTATTTTGTTGCCAACTGCTTTTTTGTTGTATTT
TGCCGTTATTTTCCGCTGGTGTAAATAGATTGTGAAGCTCCTGTATTATTTGGTTACCTA
AGAACGGACGTGATGTAATTGTTTCTTCCCACTTCTCTCCAGCGTTTTGTTCTATCGCTG
CGTTTGTGAATCGGTGCTAAGCAATAAGGCACACCTGTAACC
| PIRSF |
Notch (IPR008297) - T[1-463] 2.4E-181 - T[425-1594] 2.6E-291 |
| ProSiteProfiles |
EGF-like_dom (IPR000742) - T[1-31] 15.564 - T[33-69] 22.991 - T[71-107] 22.57 - T[109-145] 22.171 - T[147-183] 21.731 - T[193-229] 15.561 - T[231-267] 24.114 - T[269-305] 24.059 - T[307-343] 23.588 - T[345-383] 17.818 - T[385-424] 20.834 - T[426-459] 7.319 |
| Pfam |
EGF-like_dom (IPR000742) - T[2-27] 3.3E-7 - T[37-66] 6.7E-7 - T[151-180] 3.7E-8 - T[200-227] 2.9E-7 - T[235-265] 2.6E-7 - T[273-303] 3.3E-9 - T[349-380] 6.4E-6 - T[389-422] 5.6E-5 |
| SMART |
EGF-like_Ca-bd_dom (IPR001881) - T[3-31] 3.7E-4 - T[33-69] 1.1E-12 - T[71-107] 2.9E-10 - T[109-145] 9.2E-9 - T[148-183] 0.0031 - T[189-229] 0.0083 - T[231-267] 2.3E-11 - T[269-305] 2.9E-10 - T[307-343] 2.5E-12 - T[345-383] 2.3E-8 - T[389-424] 0.009 |
| SMART |
EGF-like_dom (IPR000742) - T[3-31] 0.034 - T[36-69] 3.3E-8 - T[74-107] 6.8E-6 - T[112-145] 3.6E-6 - T[150-183] 6.7E-6 - T[188-229] 2.7E-5 - T[234-267] 8.3E-7 - T[272-305] 6.5E-8 - T[310-343] 2.4E-7 - T[348-383] 2.4E-5 - T[388-424] 4.7E-8 - T[429-459] 40.0 |
| ProSitePatterns |
EGF-type_Asp/Asn_hydroxyl_site (IPR000152) - T[10-21] . - T[48-59] . - T[86-97] . - T[246-257] . - T[284-295] . - T[322-333] . |
| ProSitePatterns |
EGF-like_CS (IPR013032) - T[19-30] . - T[19-30] . - T[57-68] . - T[57-68] . - T[95-106] . - T[95-106] . - T[133-144] . - T[133-144] . - T[171-182] . - T[171-182] . - T[217-228] . - T[217-228] . - T[255-266] . - T[255-266] . - T[293-304] . - T[331-342] . - T[331-342] . - T[371-382] . - T[371-382] . - T[412-423] . - T[412-423] . - T[447-458] . |
| ProSitePatterns |
EGF_Ca-bd_CS (IPR018097) - T[33-57] . - T[231-255] . - T[307-331] . |
| SUPERFAMILY |
Growth_fac_rcpt_cys_sf (IPR009030) - T[58-189] 2.04E-12 - T[219-350] 9.1E-12 |
| Pfam |
EGF-like_CS (IPR013032) - T[80-101] 5.6E-6 - T[316-337] 8.4E-6 |
| Pfam |
EGF-like_Ca-bd_dom (IPR001881) - T[109-142] 1.5E-4 |
| SMART |
Notch_dom (IPR000800) - T[477-515] 1.0E-12 - T[518-557] 5.8E-17 - T[558-597] 2.1E-8 |
| SUPERFAMILY |
Notch-like_dom_sf (IPR035993) - T[483-515] 1.23E-6 - T[525-557] 1.44E-7 - T[564-597] 1.02E-6 |
| Pfam |
Notch_dom (IPR000800) - T[483-515] 7.3E-8 - T[522-557] 2.0E-12 - T[562-597] 1.8E-9 |
| ProSiteProfiles |
Notch_dom (IPR000800) - T[484-524] 13.711 - T[525-566] 14.97 - T[567-606] 12.525 |
| PRINTS |
Notch_dom (IPR000800) - T[502-515] 5.1E-12 - T[544-556] 5.1E-12 - T[584-596] 5.1E-12 |
| SMART |
Notch_NOD_dom (IPR010660) - T[601-657] 2.0E-13 |
| Pfam |
Notch_NOD_dom (IPR010660) - T[601-653] 3.0E-12 |
| SMART |
Notch_NODP_dom (IPR011656) - T[695-757] 7.5E-18 |
| Pfam |
Notch_NODP_dom (IPR011656) - T[696-752] 1.4E-14 |
| CDD |
Ankyrin_rpt-contain_dom (IPR020683) - T[918-1040] 9.98801E-14 - T[1014-1140] 8.89963E-32 |
| SUPERFAMILY |
Ankyrin_rpt-contain_sf (IPR036770) - T[919-1175] 6.8E-54 |
| Gene3D |
Ankyrin_rpt-contain_sf (IPR036770) - T[922-1184] 6.3E-76 |
| SMART |
Ankyrin_rpt (IPR002110) - T[930-981] 310.0 - T[986-1015] 5.5E-4 - T[1019-1049] 0.34 - T[1053-1082] 0.49 - T[1086-1115] 4.4E-4 - T[1119-1148] 0.052 |
| ProSiteProfiles |
Ankyrin_rpt-contain_dom (IPR020683) - T[964-1172] 51.542 |
| ProSiteProfiles |
Ankyrin_rpt (IPR002110) - T[986-1018] 13.517 - T[1053-1085] 10.205 - T[1086-1118] 11.594 - T[1119-1151] 10.286 |
| Pfam |
Ankyrin_rpt-contain_dom (IPR020683) - T[1068-1150] 6.1E-11 |
| SMART |
DUF3454_notch (IPR024600) - T[1500-1571] 3.1E-21 |
| Pfam |
DUF3454_notch (IPR024600) - T[1501-1570] 3.3E-21 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| NOTC3_HUMAN | 41.907 % | 900 | 0 |
| NOTC2_HUMAN | 40.251 % | 1105 | 0 |
| NOTC1_HUMAN | 41.491 % | 1105 | 0 |