Name

bFGF

Targeted Gene

(FGF16; FGF20; FGF9)

Family

Sequence-based

Type

agonist

Supplier

n/a

Comment

Recombinant human basic FGF, used to mimick the activation of several Ciona FGFs, including FGF9/16/20

Regulation

Gain of function

Publication

Hashimoto et al. (2011). The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos. Development 138(12):2591-600

Ohta et al. (2015). A Boolean Function for Neural Induction Reveals a Critical Role of Direct Intercellular Interactions in Patterning the Ectoderm of the Ascidian Embryo. PLoS Comput. Biol. 11(12):e1004687

Pasini et al. (2012). Antagonizing retinoic acid and FGF/MAPK pathways control posterior body patterning in the invertebrate chordate Ciona intestinalis. PLoS ONE 7(9):e46193

Kumano et al. (2006). Overlapping expression of FoxA and Zic confers responsiveness to FGF signaling to specify notochord in ascidian embryos. Dev Biol 300(2):770-84