- Region 'REG00000235' >
- Molecular Tool 'Zicl>NLS:Elk:WRPW' >
- Molecular Tool 'Dmrt>TGF-βR(CA)' >
- Molecular Tool 'Dmrt>BMPR1(CA)'
Molecular tool card for 'Dmrt>BMPR1(CA)'
Name
Dmrt>BMPR1(CA)
Targeted Gene
Family
Sequence-based
Type
overexpression_construct
Supplier
n/a
Comment
Dmrt regulatory region (sequence below) drives a constitutively active form of the BMP receptor (BMPR1CA) for cell-autonomous activation of BMP signalling. In these experiments, activation is restricted to Dmrt+ cells, which form the anterior neural plate and adjacent anterior ectoderm.
Regulation
Gain of function
>KhS544:4240-5239_Dmrttagtagggtggaggaagatgggacacctttggcacata
atatccaaatatccttaccccgttttacacaattaacagcggtatatgggagtcgtaaga
attccgttttataattatttgcatgttctttgtttgctactaaattggacgacaaaatgt
agtcaaaaggtgtctaatcttcccctaccctactatacgacttggggcatagttataaag
ttattccgtttcatttcttggcgttaacccgacgatcagtaattaacgatattcttcata
aataaataatgcgagaactgcaacaggactagggaagttacttaagcgagcatgtgatta
gaaattgccactgaagcactttaaaatgccgccaaaacacatacaccttcatgacacatt
gttttacagaatctcaatttaaaacccgtcgacaattatcggatttccgccgcagagtca
caggaagttgttttgcttaataatacttgttttagataagctgttatgttgctcaatgaa
taacaataatgtttacgttggttgttgtggcaatgtacattgtaacttccacaaacctct
cagagggcaaacacattaagcaaactgaatttgccaagtacttcgggaagtcactgataa
gcggacaatacgaagcgatcacagggaattgtcgcacgccagaatgtaaacaaaaacatc
gcctgtgcaccgcgcgatcgaagacacacagcgctgactaattgaccaacacaaaagcga
ggaaagaaaaaaaagcgaaaacgagaacgggatattaattgtacacgattgtgacgtaaa
ttcgaggcattttttcttccgaaatcgagcggtttaaatacctcgcgtctttattaggta
caatcatattgccttgataccttgcttagaacagtgaatacatataaatcgtattaaaag
ctttagagtgttaaaccaaagagttacagaaattatagcaaacagttcgtttaactggca
tg