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- Molecular Tool 'FoxC>DN_FGFR'
Molecular tool card for 'FoxC>DN_FGFR'
Name
FoxC>DN_FGFR
Targeted Gene
Family
Sequence-based
Type
overexpression_construct
Supplier
n/a
Comment
The minimal promoter of FoxC (REG00001205) drives the expression of a dominant negative FGF receptor in the palps lineage. This dominant-negative FGF receptor lacks the intracellular tyrosine kinase domain and its misexpression perturbs FGF-MAPK signaling.
Regulation
Loss of function
No sequence