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  1. Transcript 'Phmamm.CG.MTP2014.S1...'
  2. Molecular Tool 'Ci-ZF383-MO'
  3. Transcript 'Cisavi.CG.ENS81.R23....'
  4. Transcript 'Phmamm.CG.MTP2014.S3...'
  5. Molecular Tool 'FoxC>DN_FGFR'

Molecular tool card for 'FoxC>DN_FGFR'

Name

FoxC>DN_FGFR

Targeted Gene

(FGF16; FGF20; FGF9)

Family

Sequence-based

Type

overexpression_construct

Supplier

n/a

Comment

The minimal promoter of FoxC (REG00001205) drives the expression of a dominant negative FGF receptor in the palps lineage. This dominant-negative FGF receptor lacks the intracellular tyrosine kinase domain and its misexpression perturbs FGF-MAPK signaling.

Regulation

Loss of function

Sequence

No sequence





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