Name

RGdeltaGAP RNA

Targeted Gene

(DAB2IP; RASA1; RASAL2)

Family

Sequence-based

Type

overexpression_construct

Supplier

n/a

Comment

RGΔGAP is a dominant negative RasGAP. It was generated by PCR amplifying cDNA fragments corresponding to amino acids 1 to 585 using cDNA clone cibd054f08 (Satou et al., 2002) and subcloning into pRN3 (Lemaire et al., 1995).

Regulation

Loss of function

Publication

Haupaix et al. (2013). p120RasGAP mediates ephrin/Eph-dependent attenuation of FGF/ERK signals during cell fate specification in ascidian embryos. Development 140(21):4347-52