- EST 'AHC0AAA140YM02_RM1' >
- Molecular Tool 'Etr>Onecut-WRPW (D'Aniello 2011)'
Molecular tool card for 'Etr>Onecut-WRPW (D'Aniello 2011)'
Name
Etr>Onecut-WRPW (D'Aniello 2011)
Targeted Gene
Family
Sequence-based
Type
overexpression_construct
Supplier
Comment
Constitutively activated Onecut driven throughout the nervous system by the ETR enhancer.
The Etr (KH.C6.128) promoter fragment and the Ci-Onecut coding sequence replaced the MESP promoter and the coding sequence of Ets in the MESP>Ets:VP16 overexpression construct (Davidson 2006)
Regulation
Loss of function
ConstitutivelyinactivatedOnecutdriventhroughoutthenervoussys
tembytheETRenhancer.
TheEtr(KH.C6.128)promoterfragmentand
theCi-OnecutcodingsequencereplacedtheMESPpromoterandthecodin
gsequenceofEtsintheMESP>Ets:WRPWoverexpressionconstruct(Davi
dson2006)